Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | BRD2 | P25440 | 1/20 | 0.40 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.35 |
| ▸ | PARG | Q86W56 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6582730 | 0.79 | ALDH1A1 (0.45) | BRD4BRD2BRD3MAPTLMNA | |
| SCHEMBL21439090 | 0.73 | ALDH1A1 (0.56) | MAPTLMNASMN1; SMN2KDM4EMEN1 | |
| SCHEMBL21439584 | 0.71 | KDM4E (0.65) | BRD4MAPTLMNASMN1; SMN2KDM4E | |
| SCHEMBL21028198 | 0.70 | ALDH1A1 (0.43) | BRD4BRD2BRD3MAPTLMNA | |
| SCHEMBL12545456 | 0.69 | ACHE (0.40) | — | |
| SCHEMBL19590542 | 0.68 | MEN1 (0.42) | BRD4BRD2BRD3MAPTLMNA | |
| SCHEMBL17024493 | 0.67 | ACHE (0.33) | LMNAHPGDPOLB | |
| SCHEMBL19590545 | 0.67 | CNR1 (0.36) | MAPTLMNASMN1; SMN2KDM4EMEN1 | |
| SCHEMBL30714356 | 0.67 | CA1 (0.44) | MAPTLMNASMN1; SMN2KDM4EMEN1 | |
| SCHEMBL21028383 | 0.66 | ALDH1A1 (0.44) | BRD4BRD2BRD3MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3649120-A1 | TRIAZOLE DERIVATIVES USED AS A HYPOXIA IMAGING AGENT | Centre National De La Recherche Scientifique (FR) | 2020-05-13 | — | — | EP | disclosed |