Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.72 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.72 |
| ▸ | LMNA | P02545 | 4/20 | 0.70 |
| ▸ | HPGD | P15428 | 1/20 | 0.70 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.70 |
| ▸ | POLB | P06746 | 2/20 | 0.69 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.68 |
| ▸ | SLC18A3 | Q16572 | 3/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | KLK7 | P49862 | 1/20 | 0.63 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.63 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21926983 | 1.00 | ALDH1A1 (0.72) | ALDH1A1SMN1; SMN2LMNAHPGDHIF1A | |
| SCHEMBL21926385 | 0.95 | ALDH1A1 (0.79) | ALDH1A1SMN1; SMN2LMNAHPGDHIF1A | |
| SCHEMBL21926998 | 0.89 | ALDH1A1 (0.74) | ALDH1A1SMN1; SMN2LMNAHPGDHIF1A | |
| SCHEMBL21926989 | 0.89 | MGLL (0.74) | ALDH1A1SMN1; SMN2LMNAHPGDHIF1A | |
| SCHEMBL5470401 | 0.89 | ALDH1A1 (0.74) | ALDH1A1SMN1; SMN2LMNAHPGDHIF1A | |
| SCHEMBL21928853 | 0.89 | MEN1 (0.75) | ALDH1A1SMN1; SMN2LMNAHPGDHIF1A | |
| SCHEMBL21926380 | 0.89 | MEN1 (0.72) | ALDH1A1SMN1; SMN2LMNAPOLBMAPK1 | |
| SCHEMBL21926833 | 0.89 | MGLL (0.74) | ALDH1A1SMN1; SMN2LMNAHPGDHIF1A | |
| SCHEMBL5470399 | 0.89 | ALDH1A1 (0.74) | ALDH1A1SMN1; SMN2LMNAHPGDHIF1A | |
| SCHEMBL5479680 | 0.88 | ALDH1A1 (0.62) | ALDH1A1LMNAHPGDMAPK1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200131125-A1 | ARYL-PIPERIDINE DERIVATIVES | ARTAX BIOPHARMA INC. | 2020-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200131125-A1 | ARYL-PIPERIDINE DERIVATIVES | CD4, CD2, CCR1 | ALDH1A1 1450/4885SMN1; SMN2 4010/4885LMNA 3259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.