SCHEMBL21926366

SCHEMBL21926366

Clc1cccc2c1oc1cc(-c3nc(-c4ccccc4)nc(-c4ccc5c(c4)oc4ccccc45)n3)ccc12

nearest known ligand 0.45

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
AHR P35869 6/20 0.45
TTR P02766 4/20 0.45
MAPT P10636 5/20 0.40
ALDH1A1 P00352 4/20 0.40
HPGD P15428 3/20 0.40
POLB P06746 2/20 0.40
NPSR1 Q6W5P4 2/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
ALOX5 P09917 1/20 0.40
LMNA P02545 1/20 0.40
GAA P10253 1/20 0.40
KDM4E B2RXH2 2/20 0.39
TSHR P16473 1/20 0.39
PIM1 P11309 1/20 0.38
CSNK2A2 P19784 1/20 0.38
CSNK2B P67870 1/20 0.38
PIM3 Q86V86 1/20 0.38
PIM2 Q9P1W9 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26779585 0.97 TTR (0.47) AHRTTRMAPTALDH1A1HPGD
SCHEMBL21926810 0.96 AHR (0.46) AHRTTRMAPTALDH1A1HPGD
SCHEMBL23824076 0.96 TTR (0.46) AHRTTRMAPTALDH1A1HPGD
SCHEMBL21191839 0.94 TTR (0.43) AHRTTRMAPTALDH1A1HPGD
SCHEMBL23203691 0.92 ALOX5 (0.40) AHRTTRMAPTALDH1A1HPGD
SCHEMBL23819567 0.91 AHR (0.42) AHRTTRMAPTALDH1A1HPGD
SCHEMBL21645332 0.89 TTR (0.47) AHRTTRMAPTALDH1A1HPGD
SCHEMBL23820547 0.89 AHR (0.40) AHRTTRMAPTALDH1A1HPGD
SCHEMBL21192182 0.88 AHR (0.46) AHRTTRMAPTALDH1A1HPGD
SCHEMBL23203877 0.88 PIM1 (0.46) AHRTTRMAPTALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11873297-B2 Compound and organic light emitting device comprising the same LG CHEM, LTD. (KR) 2024-01-16 US disclosed
US-11873297-B2 Compound and organic light emitting device comprising the same LG CHEM, LTD. (KR) 2024-01-16 US disclosed
US-11807632-B2 Heterocyclic compound and organic light emitting device comprising the same LG CHEM, LTD. (KR) 2023-11-07 US disclosed
US-11807632-B2 Heterocyclic compound and organic light emitting device comprising the same LG CHEM, LTD. (KR) 2023-11-07 US disclosed
EP-3770157-B1 NOVEL HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME LG CHEMICAL LTD (KR) 2022-05-04 EP disclosed
US-20210323948-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME LG CHEM, LTD. (KR) 2021-10-21 US disclosed
US-20210139469-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME LG CHEM, LTD. (KR) 2021-05-13 US disclosed
EP-3770157-A1 NOVEL HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DIODE USING SAME LG CHEM, LTD. (KR) 2021-01-27 EP disclosed
WO-2020085740-A1 NOVEL HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DIODE USING SAME 주식회사 엘지화학 2020-04-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11807632-B2 Heterocyclic compound and organic light emitting device comprising the same ARNT, AHR, DRD1 AHR 2/4885TTR 4498/4885MAPT 1507/4885
US-20210323948-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME CCNL2, UBE2L3, OPRL1 AHR 39/4885TTR 4378/4885MAPT 3639/4885
US-20210139469-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DEVICE COMPRISING THE SAME ARNT, AHR, DRD1 AHR 2/4885TTR 4498/4885MAPT 1507/4885
US-11873297-B2 Compound and organic light emitting device comprising the same CCNL2, UBE2L3, ARL1 AHR 44/4885TTR 4313/4885MAPT 3608/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.