Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.45 |
| ▸ | CLPP | Q16740 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5480132 | 0.91 | ALDH1A1 (0.52) | HSD11B1RAB9AALDH1A1MAPTKMT2A | |
| SCHEMBL5480130 | 0.91 | ALDH1A1 (0.52) | HSD11B1RAB9AALDH1A1MAPTKMT2A | |
| SCHEMBL5474311 | 0.81 | HSD11B1 (0.68) | HSD11B1RAB9AALDH1A1KMT2AMEN1 | |
| SCHEMBL5474315 | 0.81 | HSD11B1 (0.68) | HSD11B1RAB9AALDH1A1KMT2AMEN1 | |
| SCHEMBL21926849 | 0.79 | ALDH1A1 (0.67) | HSD11B1RAB9AALDH1A1MAPTKMT2A | |
| SCHEMBL21928849 | 0.77 | HSD11B1 (0.71) | HSD11B1RAB9AALDH1A1KMT2AMEN1 | |
| SCHEMBL192998 | 0.76 | NPC1 (0.60) | HSD11B1RAB9AALDH1A1MAPTKMT2A | |
| SCHEMBL191835 | 0.76 | NPC1 (0.60) | HSD11B1RAB9AALDH1A1MAPTKMT2A | |
| SCHEMBL5479819 | 0.76 | HSD11B1 (0.60) | HSD11B1RAB9AALDH1A1GAAGLA | |
| SCHEMBL3589879 | 0.75 | GLA (0.75) | HSD11B1RAB9AALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200131125-A1 | ARYL-PIPERIDINE DERIVATIVES | ARTAX BIOPHARMA INC. | 2020-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200131125-A1 | ARYL-PIPERIDINE DERIVATIVES | CD4, CD2, CCR1 | HSD11B1 4689/4885RAB9A 2963/4885ALDH1A1 1450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.