Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28014648 | 0.69 | MAOB (0.36) | MAOBMAOA | |
| SCHEMBL5422674 | 0.63 | — | — | |
| SCHEMBL19717559 | 0.56 | MAOB (0.42) | MAOBMAOA | |
| SCHEMBL12477787 | 0.56 | MAOB (0.67) | MAOBMAOA | |
| SCHEMBL28079324 | 0.56 | MAOB (0.43) | MAOBMAOA | |
| SCHEMBL7564380 | 0.56 | RECQL (0.33) | MAOBMAOA | |
| SCHEMBL7409988 | 0.55 | OPRM1 (0.30) | — | |
| SCHEMBL4926456 | 0.55 | MAOB (0.37) | MAOBMAOA | |
| SCHEMBL10634176 | 0.55 | MAOB (0.41) | MAOBMAOA | |
| SCHEMBL27906055 | 0.53 | MAOB (0.34) | MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11555012-B2 | ACLY inhibitors and uses thereof | Nimbus Artemis, Inc. (US) | 2023-01-17 | — | — | US | disclosed |
| US-20200148634-A1 | ACLY INHIBITORS AND USES THEREOF | Nimbus Artemis, Inc. | 2020-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200148634-A1 | ACLY INHIBITORS AND USES THEREOF | ACLY, ATP5ME, ATP5MG | MAOB 3225/4885MAOA 3294/4885 |
| US-11555012-B2 | ACLY inhibitors and uses thereof | ACLY, ATP5ME, ATP5MG | MAOB 3225/4885MAOA 3294/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.