SCHEMBL219317

SCHEMBL219317

CCc1ccccc1C1=Cc2ccccc2[CH]1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.36
CSNK2A2 P19784 1/20 0.36
CSNK2B P67870 1/20 0.36
CSNK2A1 P68400 1/20 0.36
CSNK2A3 Q8NEV1 1/20 0.36
GABRA1 P14867 2/20 0.34
GABRB2 P47870 2/20 0.34
TRPA1 O75762 1/20 0.33
LMNA P02545 3/20 0.33
RPS6KA2 Q15349 1/20 0.33
PTPRC P08575 2/20 0.33
CDC25B P30305 1/20 0.33
MGLL Q99685 1/20 0.32
SLC9A1 P19634 1/20 0.32
PDK2 Q15119 1/20 0.32
NR1H2 P55055 1/20 0.32
NR1H3 Q13133 1/20 0.32
ALDH1A1 P00352 2/20 0.32
MAPT P10636 2/20 0.32
NPC1 O15118 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL217632 0.86 GABRA1 (0.34) CYP2D6GABRA1GABRB2PDK2
SCHEMBL216311 0.85 NR1H2 (0.33) NR1H2NR1H3PTPN1
SCHEMBL216178 0.76 KDM4E (0.31) NR1H2NR1H3ALDH1A1KDM4EHPGD
SCHEMBL218457 0.74 NPC1 (0.38) ALDH1A1NPC1RAB9ASMN1; SMN2KDM4E
SCHEMBL198461 0.73 CSNK2A2 (0.52) CYP2D6CSNK2A2CSNK2BCSNK2A1CSNK2A3
SCHEMBL2965010 0.73
SCHEMBL2971734 0.72 KMT2A (0.33) PTPRCMAPK1MEN1ALOX15KMT2A
SCHEMBL2975147 0.72 PTPRC (0.30) PTPRC
SCHEMBL2967277 0.72
SCHEMBL11382359 0.71 CSNK2A2 (0.50) CYP2D6CSNK2A2CSNK2BCSNK2A1CSNK2A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10421921-B2 Lubricants from mixed alpha-olefin feeds EXXONMOBIL CHEMICAL PATENTS INC. (US) 2019-09-24 US disclosed
EP-1920031-B1 LUBRICANTS FROM MIXED ALPHA-OLEFIN FEEDS EXXONMOBIL CHEMICAL PATENTS INC (US) 2018-01-10 EP disclosed
US-20170137737-A1 Lubricants from Mixed Alpha-Olefin Feeds EXXONMOBIL CHEMICAL PATENTS INC. 2017-05-18 US disclosed
US-9593288-B2 Lubricants from mixed alpha-olefin feeds EXXONMOBIL CHEMICAL PATENTS INC. (US) 2017-03-14 US disclosed
US-9409834-B2 Low viscosity poly-alpha-olefins EXXONMOBIL CHEMICAL PATENTS INC. (US) 2016-08-09 US disclosed
US-20150252279-A1 Lubricants From Mixed Alpha-Olefin Feeds EXXONMOBIL CHEMICAL PATENTS INC. 2015-09-10 US disclosed
US-8957159-B2 Multiple catalyst system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2015-02-17 US disclosed
US-8921291-B2 Lubricants from mixed alpha-olefin feeds EXXONMOBIL CHEMICAL PATENTS INC. (US) 2014-12-30 US disclosed
US-20140378720-A1 Processes to Produce Polyalpha-Olefin Compositions EXXONMOBIL CHEMICAL PATENTS INC. 2014-12-25 US disclosed
EP-1910432-B1 PROCESS TO PRODUCE LOW VISCOSITY POLY-ALPHA-OLEFINS EXXONMOBIL CHEM PATENTS INC (US) 2014-11-12 EP disclosed
US-20090005279-A1 Polyalpha-Olefin Compositions and Processes to Produce the Same EXXONMOBIL CHEMICAL PATENTS INC. 2009-01-01 US disclosed
WO-2008140875-A1 CATALYST SYSTEM FOR OLEFIN POLYMERIZATION AND POLYMERS PRODUCED THEREFROM EXXONMOBIL CHEMICAL PATENTS INC. (US) 2008-11-20 WO disclosed
US-20080287617-A1 Catalyst System For Olefin Polymerization And Polymers Produced Therefrom EXXONMOBIL CHEMICAL PATENTS INC. 2008-11-20 US disclosed
US-20080177121-A1 Process to produce high viscosity fluids EXXONMOBIL CHEMICAL PATENTS INC. 2008-07-24 US disclosed
US-20070293640-A1 Multiple catalyst system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. 2007-12-20 US disclosed
US-7294681-B2 Mutliple catalyst system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-11-13 US disclosed
US-7223822-B2 Multiple catalyst and reactor system for olefin polymerization and polymers produced therefrom EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-05-29 US disclosed
US-20070043248-A1 Process to produce low viscosity poly-alpha-olefins EXXONMOBIL CHEMICAL PATENTS INC. 2007-02-22 US disclosed
EP-1017730-A2 INJECTION MOULDING ARTICLES MADE OF METALLOCENE AND POLYPROPYLENE Basell Polyolefine GmbH (DE) 2000-07-12 EP disclosed
WO-1999011678-A2 INJECTION MOULDING ARTICLES MADE OF METALLOCENE AND POLYPROPYLENE TARGOR GMBH (DE) 1999-03-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070043248-A1 Process to produce low viscosity poly-alpha-olefins AP1M1, AP3D1, AP3M1 CYP2D6 4109/4885CSNK2A2 2638/4885CSNK2B 2788/4885
US-20080177121-A1 Process to produce high viscosity fluids SCO2, POLI, TAOK1 CYP2D6 4809/4885CSNK2A2 140/4885CSNK2B 332/4885
US-20140378720-A1 Processes to Produce Polyalpha-Olefin Compositions AP1M1, AP1S1, CCT4 CYP2D6 3650/4885CSNK2A2 827/4885CSNK2B 1495/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.