SCHEMBL21931874

SCHEMBL21931874

Cc1ccc(S(=O)(=O)N(C)c2ccc(C=C3CCn4c3nc(=O)c3ccccc34)cc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SMARCA4 P51532 6/20 0.57
▸ PBRM1 Q86U86 4/20 0.51
▸ PER2 O15055 1/20 0.44
▸ CRY1 Q16526 1/20 0.44
▸ CRY2 Q49AN0 1/20 0.44
▸ CA12 O43570 1/20 0.44
▸ CA9 Q16790 1/20 0.44
▸ MAPT P10636 2/20 0.43
▸ MCOLN3 Q8TDD5 1/20 0.43
▸ HTT P42858 2/20 0.42
▸ MEN1 O00255 1/20 0.42
▸ RECQL P46063 1/20 0.42
▸ KMT2A Q03164 1/20 0.42
▸ NPSR1 Q6W5P4 1/20 0.42
▸ L3MBTL1 Q9Y468 1/20 0.42
▸ POLB P06746 1/20 0.41
▸ CCR3 P51677 1/20 0.41
▸ NPC1 O15118 1/20 0.39
▸ RAB9A P51151 1/20 0.39
▸ C1R P00736 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21931873 1.00 SMARCA4 (0.57) SMARCA4PBRM1PER2CRY1CRY2
SCHEMBL30139674 1.00 SMARCA4 (0.57) SMARCA4PBRM1PER2CRY1CRY2
SCHEMBL30859441 1.00 SMARCA4 (0.57) SMARCA4PBRM1PER2CRY1CRY2
SCHEMBL20704878 0.86 SMARCA4 (0.49) SMARCA4PBRM1MAPTMEN1KMT2A
SCHEMBL20704877 0.86 SMARCA4 (0.49) SMARCA4PBRM1MAPTMEN1KMT2A
SCHEMBL25053615 0.84 SMARCA4 (0.58) SMARCA4PBRM1CCR3NPC1RAB9A
SCHEMBL30859440 0.83 SMARCA4 (0.52) SMARCA4PBRM1MEN1KMT2AL3MBTL1
SCHEMBL20704901 0.83 SMARCA4 (0.52) SMARCA4PBRM1MEN1KMT2AL3MBTL1
SCHEMBL20704903 0.83 SMARCA4 (0.52) SMARCA4PBRM1CA12CA9MAPT
SCHEMBL21992747 0.81 SMARCA4 (0.58) SMARCA4PBRM1CCR3NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260060985-A1 Compounds for the Prevention and Treatment of Medical Disorders and Uses Thereof GALECTIN SCIENCES, LLC (US) 2026-03-05 — — US disclosed
US-12377102-B2 Compounds for the prevention and treatment of medical disorders and uses thereof GALECTIN SCIENCES, LLC (US) 2025-08-05 — — US disclosed
US-20230116370-A1 Compounds for the Prevention and Treatment of Medical Disorders and Uses Thereof GALECTIN SCIENCES, LLC 2023-04-13 — — US disclosed
US-11583530-B2 Compounds for the prevention and treatment of medical disorders and uses thereof GALECTIN SCIENCES, LLC (US) 2023-02-21 — — US disclosed
US-20200147088-A1 Compounds for the Prevention and Treatment of Medical Disorders and Uses Thereof GALECTIN SCIENCES, LLC 2020-05-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260060985-A1 Compounds for the Prevention and Treatment of Medical Disorders and Uses Thereof LGALS3, LGALS1, LGALS2 SMARCA4 4289/4885PBRM1 3332/4885PER2 3453/4885
US-20230116370-A1 Compounds for the Prevention and Treatment of Medical Disorders and Uses Thereof LGALS1, LGALS2, LGALS3 SMARCA4 4569/4885PBRM1 4399/4885PER2 3913/4885
US-20200147088-A1 Compounds for the Prevention and Treatment of Medical Disorders and Uses Thereof LGALS1, LGALS2, LGALS3 SMARCA4 4569/4885PBRM1 4399/4885PER2 3913/4885
US-11583530-B2 Compounds for the prevention and treatment of medical disorders and uses thereof LGALS1, LGALS2, LGALS3 SMARCA4 4569/4885PBRM1 4399/4885PER2 3913/4885
US-12377102-B2 Compounds for the prevention and treatment of medical disorders and uses thereof LGALS1, LGALS2, LGALS3 SMARCA4 4569/4885PBRM1 4399/4885PER2 3913/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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