SCHEMBL21931876

SCHEMBL21931876

Cc1ccc(CSc2ccc(/C=C3\CCn4c3nc(=O)c3ccccc34)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ SMARCA4 P51532 6/20 0.53
▸ PBRM1 Q86U86 4/20 0.53
▸ CCR3 P51677 2/20 0.41
▸ MEN1 O00255 3/20 0.41
▸ KMT2A Q03164 3/20 0.41
▸ RAB9A P51151 2/20 0.40
▸ NPC1 O15118 1/20 0.40
▸ BLM P54132 1/20 0.38
▸ ALDH1A1 P00352 1/20 0.38
▸ MAPT P10636 1/20 0.38
▸ HTT P42858 1/20 0.38
▸ SMN1; SMN2 Q16637 1/20 0.38
▸ ALOX5 P09917 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30859443 1.00 SMARCA4 (0.53) SMARCA4PBRM1CCR3MEN1KMT2A
SCHEMBL25053621 1.00 SMARCA4 (0.53) SMARCA4PBRM1CCR3MEN1KMT2A
SCHEMBL21992747 0.88 SMARCA4 (0.58) SMARCA4PBRM1CCR3RAB9ANPC1
SCHEMBL21992948 0.87 SMARCA4 (0.48) SMARCA4PBRM1CCR3MEN1KMT2A
SCHEMBL21992771 0.86 PBRM1 (0.64) SMARCA4PBRM1CCR3RAB9ANPC1
SCHEMBL21993759 0.84 SMARCA4 (0.61) SMARCA4PBRM1CCR3MEN1KMT2A
SCHEMBL21931877 0.83 SMARCA4 (0.53) SMARCA4PBRM1CCR3KMT2ARAB9A
SCHEMBL20704901 0.82 SMARCA4 (0.52) SMARCA4PBRM1CCR3MEN1KMT2A
SCHEMBL30859440 0.82 SMARCA4 (0.52) SMARCA4PBRM1CCR3MEN1KMT2A
SCHEMBL21992960 0.81 SMARCA4 (0.60) SMARCA4PBRM1CCR3MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260060985-A1 Compounds for the Prevention and Treatment of Medical Disorders and Uses Thereof GALECTIN SCIENCES, LLC (US) 2026-03-05 — — US disclosed
US-12377102-B2 Compounds for the prevention and treatment of medical disorders and uses thereof GALECTIN SCIENCES, LLC (US) 2025-08-05 — — US disclosed
US-20230116370-A1 Compounds for the Prevention and Treatment of Medical Disorders and Uses Thereof GALECTIN SCIENCES, LLC 2023-04-13 — — US disclosed
US-11583530-B2 Compounds for the prevention and treatment of medical disorders and uses thereof GALECTIN SCIENCES, LLC (US) 2023-02-21 — — US disclosed
US-11583530-B2 Compounds for the prevention and treatment of medical disorders and uses thereof GALECTIN SCIENCES, LLC (US) 2023-02-21 — — US disclosed
US-20200147088-A1 Compounds for the Prevention and Treatment of Medical Disorders and Uses Thereof GALECTIN SCIENCES, LLC 2020-05-14 — — US disclosed
US-20200147088-A1 Compounds for the Prevention and Treatment of Medical Disorders and Uses Thereof GALECTIN SCIENCES, LLC 2020-05-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260060985-A1 Compounds for the Prevention and Treatment of Medical Disorders and Uses Thereof LGALS3, LGALS1, LGALS2 SMARCA4 4289/4885PBRM1 3332/4885CCR3 99/4885
US-20230116370-A1 Compounds for the Prevention and Treatment of Medical Disorders and Uses Thereof LGALS1, LGALS2, LGALS3 SMARCA4 4569/4885PBRM1 4399/4885CCR3 752/4885
US-20200147088-A1 Compounds for the Prevention and Treatment of Medical Disorders and Uses Thereof LGALS1, LGALS2, LGALS3 SMARCA4 4569/4885PBRM1 4399/4885CCR3 752/4885
US-11583530-B2 Compounds for the prevention and treatment of medical disorders and uses thereof LGALS1, LGALS2, LGALS3 SMARCA4 4569/4885PBRM1 4399/4885CCR3 752/4885
US-12377102-B2 Compounds for the prevention and treatment of medical disorders and uses thereof LGALS1, LGALS2, LGALS3 SMARCA4 4569/4885PBRM1 4399/4885CCR3 752/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback