SCHEMBL219324

SCHEMBL219324

COc1ccc2ncccc2c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDGFRB P09619 2/20 0.59
PDGFRA P16234 2/20 0.59
ALDH1A1 P00352 6/20 0.58
CYP3A4 P08684 1/20 0.58
RAB9A P51151 5/20 0.57
NPC1 O15118 4/20 0.57
POLB P06746 2/20 0.57
EGFR P00533 1/20 0.56
CYP1A2 P05177 1/20 0.55
CYP2A6 P11509 1/20 0.55
HTT P42858 2/20 0.54
ALOX15 P16050 1/20 0.54
KDM4E B2RXH2 2/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
TP53 P04637 1/20 0.53
HSP90AA1 P07900 1/20 0.53
HSP90AB1 P08238 1/20 0.53
MAPT P10636 1/20 0.53
TSHR P16473 1/20 0.53
CASP1 P29466 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ethane SCHEMBL27318292 0.98 PDGFRB (0.58) PDGFRBPDGFRAALDH1A1CYP3A4RAB9A
Hydrochloric Acid SCHEMBL29522997 0.98 PDGFRB (0.58) PDGFRBPDGFRAALDH1A1CYP3A4RAB9A
Benzene SCHEMBL28101215 0.98 PDGFRB (0.58) PDGFRBPDGFRAALDH1A1CYP3A4RAB9A
Ammonia Solution, Strong SCHEMBL1598970 0.98 PDGFRB (0.58) PDGFRBPDGFRAALDH1A1CYP3A4RAB9A
Hydrochloric Acid SCHEMBL11881983 0.98 PDGFRB (0.58) PDGFRBPDGFRAALDH1A1CYP3A4RAB9A
Ethylene SCHEMBL27787596 0.96 PDGFRB (0.56) PDGFRBPDGFRAALDH1A1CYP3A4RAB9A
Quinoline SCHEMBL10706605 0.95 ALDH1A1 (0.59) PDGFRBPDGFRAALDH1A1CYP3A4RAB9A
Biphenyl SCHEMBL28787261 0.92 PDGFRB (0.54) PDGFRBPDGFRAALDH1A1CYP3A4RAB9A
Pyridine SCHEMBL28992130 0.92 PDGFRB (0.54) PDGFRBPDGFRAALDH1A1CYP3A4RAB9A
Ethylamine SCHEMBL28845951 0.92 CYP3A4 (0.52) PDGFRBPDGFRAALDH1A1CYP3A4RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1925 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240402157-A1 Chromogenic Absorbent Material for Animal Litter 7905122 CANADA INC. (CA) 2024-12-05 US claimed
CN-118724712-A Preparation method of organic bromine-containing compound 郑州大学 2024-10-01 CN claimed
CN-118329877-A Color developing solution for detecting active oxygen content based on visual colorimetry, kit and application 杭州澳麒生物科技有限公司 2024-07-12 CN claimed
CN-112485246-B Single epithelial tissue tumor cell seepage free heme chromogenic solution 重庆瑞卡威生物科技有限公司 2024-04-26 CN claimed
CN-113559904-B Application of nitrogen-carbon material anchored iron single-atom catalyst in catalyzing ammoxidation of alcohol to prepare nitrile 南京理工大学 2024-04-02 CN claimed
EP-4341421-A1 CHROMOGENIC ABSORBENT MATERIAL FOR ANIMAL LITTER 7905122 Canada Inc. (CA) 2024-03-27 EP claimed
CN-117530366-A Antibacterial composition and application thereof 航天神舟生物科技集团有限公司 2024-02-09 CN claimed
CN-116120921-B Fluorescent-colorimetric bimodal chloride ion probe based on luminescent gold nanoclusters and preparation method and application thereof 南方科技大学 2024-01-30 CN claimed
US-20230416786-A1 USE OF AMINOQUINOLINE COMPOUNDS FOR HIGHER GENE INTEGRATION CELLECTIS SA (FR) 2023-12-28 US claimed
CN-117164613-A Preparation method of organic luminescent material intermediate 奥盖尼克材料(苏州)有限公司 2023-12-05 CN claimed
EP-0233287-A1 1,4-THIAZINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND CARDIOTONICS CONTAINING THE SAME ZENYAKU KOGYO KABUSHIKIKAISHA (JP) 1987-08-26 EP claimed
EP-0230229-A2 Stable composition for the determination of peroxidatively active substances MILES INC. (US) 1987-07-29 EP claimed
US-4562043-A IN FECES, HYDROGEN PEROXIDE, TETRAMETHYLBENZIDINE UNITED STATES PACKAGING CORPORATION, 50Y CLAY ST., LAPORTE, IN. 46350 1985-12-31 US claimed
US-4540787-A Method of preparing trans-D1-1-alkyl-6-oxodecahydroquinolines ELI LILLY AND COMPANY (US) 1985-09-10 US claimed
EP-0043469-B1 INTERFERENCE-RESISTANT TEST DEVICE FOR DETERMINING A PEROXIDATIVELY ACTIVE SUBSTANCE IN A TEST SAMPLE AND METHOD FOR PREPARING IT MILES LABORATORIES, INC. (US) 1985-01-16 EP claimed
EP-0043469-A1 Interference-resistant test device for determining a peroxidatively active substance in a test sample and method for preparing it MILES LABORATORIES, INC. (US) 1982-01-13 EP claimed
US-4129417-A Multisystem test means MILES LABORATORIES, INC. (US) 1978-12-12 US claimed
US-4102688-A CONTAINING PYRAZOLO(3,4-B)PYRIDINE/3,6-DIONE MOIETY FUJI PHOTO FILM CO., LTD. (JP) 1978-07-25 US claimed
US-3986833-A TEST COMPOSITION, DEVICE, AND METHOD FOR THE DETECTION OF PEROXIDATIVELY ACTIVE SUBSTANCES MILES LABORATORIES, INC. (US) 1976-10-19 US claimed
US-3970461-A Fogged, direct-positive silver halide emulsion containing carbocyanine dye having indolenine nucleus FUJI PHOTO FILM CO., LTD. (JA) 1976-07-20 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230416786-A1 USE OF AMINOQUINOLINE COMPOUNDS FOR HIGHER GENE INTEGRATION ERCC4, LIG4, LIG3 PDGFRB 4224/4885PDGFRA 4108/4885ALDH1A1 2147/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.