Biphenyl

Biphenyl

SCHEMBL28787261

COc1ccc2ncccc2c1.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDGFRB P09619 2/20 0.54
PDGFRA P16234 2/20 0.54
RAB9A P51151 7/20 0.53
NPC1 O15118 6/20 0.53
POLB P06746 2/20 0.53
CYP3A4 P08684 1/20 0.52
CYP1A2 P05177 1/20 0.52
CYP2A6 P11509 1/20 0.52
ALDH1A1 P00352 4/20 0.51
CYP11B1 P15538 2/20 0.51
CYP11B2 P19099 2/20 0.51
KDM4E B2RXH2 3/20 0.50
SMN1; SMN2 Q16637 3/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
TOP1 P11387 1/20 0.50
TP53 P04637 1/20 0.50
HPGD P15428 1/20 0.50
TSHR P16473 1/20 0.50
NFKB1 P19838 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL28101215 0.93 PDGFRB (0.58) PDGFRBPDGFRARAB9ANPC1POLB
SCHEMBL219324 0.92 PDGFRB (0.59) PDGFRBPDGFRARAB9ANPC1POLB
Quinoline SCHEMBL10706605 0.90 ALDH1A1 (0.59) PDGFRBPDGFRARAB9ANPC1POLB
Ammonia Solution, Strong SCHEMBL1598970 0.90 PDGFRB (0.58) PDGFRBPDGFRARAB9ANPC1POLB
Hydrochloric Acid SCHEMBL11881983 0.90 PDGFRB (0.58) PDGFRBPDGFRARAB9ANPC1POLB
Hydrochloric Acid SCHEMBL29522997 0.90 PDGFRB (0.58) PDGFRBPDGFRARAB9ANPC1POLB
Ethane SCHEMBL27318292 0.90 PDGFRB (0.58) PDGFRBPDGFRARAB9ANPC1POLB
Ethylene SCHEMBL27787596 0.88 PDGFRB (0.56) PDGFRBPDGFRARAB9ANPC1POLB
Pyridine SCHEMBL28992130 0.87 PDGFRB (0.54) PDGFRBPDGFRARAB9ANPC1POLB
Acetic Acid SCHEMBL28050699 0.86 ALDH1A1 (0.61) PDGFRBPDGFRARAB9ANPC1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102060761-B Method for preparing quinoline UNIV ZHEJIANG 2012-10-17 CN disclosed
CN-102060761-A Method for preparing quinoline UNIV ZHEJIANG 2011-05-18 CN disclosed