Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | BRD4 | O60885 | 3/20 | 0.56 |
| ▸ | BRD2 | P25440 | 1/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 9/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | TDO2 | P48775 | 1/20 | 0.49 |
| ▸ | MT-CO2 | P00403 | 3/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CA3 | P07451 | 1/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1463375 | 0.86 | PTPN1 (0.67) | MEN1GAAKMT2ABRD4BRD2 | |
| SCHEMBL31301253 | 0.83 | PTPN1 (0.53) | MEN1GAAKMT2ABRD4BRD2 | |
| SCHEMBL14072057 | 0.81 | BRD4 (0.59) | MEN1GAAKMT2ABRD4PTGS1 | |
| SCHEMBL21932440 | 0.77 | PTPN1 (0.54) | MEN1GAAKMT2ABRD4PTGS1 | |
| SCHEMBL903110 | 0.73 | KMT2A (1.00) | MEN1GAAKMT2AALDH1A1TSHR | |
| SCHEMBL8784588 | 0.73 | MAP4K4 (0.69) | MEN1GAAKMT2ABRD4BRD2 | |
| SCHEMBL9069238 | 0.73 | BRD4 (0.66) | MEN1GAAKMT2ABRD4BRD2 | |
| 3,5-Dimethyl-4-Phenylisoxazole SCHEMBL12134072 | 0.72 | BRD4 (1.00) | BRD4BRD2PTGS2PTGS1TDO2 | |
| Hydrochloric Acid SCHEMBL30684473 | 0.72 | KMT2A (0.97) | MEN1GAAKMT2AALDH1A1TSHR | |
| Hydrochloric Acid SCHEMBL30684542 | 0.72 | KMT2A (0.97) | MEN1GAAKMT2AALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200148650-A1 | ISOXAZOLE CARBOXAMIDE COMPOUNDS | Epizyme, Inc. | 2020-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200148650-A1 | ISOXAZOLE CARBOXAMIDE COMPOUNDS | SMYD3, SMYD2, SNRPD3 | MEN1 3153/4885GAA 2747/4885KMT2A 551/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.