Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.47 |
| ▸ | IKBKB | O14920 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.44 |
| ▸ | BRD4 | O60885 | 2/20 | 0.43 |
| ▸ | TDO2 | P48775 | 1/20 | 0.43 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | DUSP3 | P51452 | 3/20 | 0.39 |
| ▸ | MAP2 | P11137 | 1/20 | 0.39 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14072057 | 0.84 | BRD4 (0.59) | PTPN1ADORA2AIKBKBMEN1GAA | |
| SCHEMBL16485987 | 0.84 | MEN1 (0.55) | PTPN1ADORA2AMEN1GAAKMT2A | |
| SCHEMBL21932437 | 0.83 | MEN1 (0.58) | PTPN1ADORA2AIKBKBMEN1GAA | |
| SCHEMBL6170435 | 0.74 | PTGS2 (0.66) | PTGS1 | |
| SCHEMBL21932440 | 0.72 | PTPN1 (0.54) | PTPN1ADORA2AIKBKBMEN1GAA | |
| SCHEMBL17292696 | 0.72 | MEN1 (0.52) | PTPN1ADORA2AIKBKBMEN1GAA | |
| SCHEMBL10432303 | 0.71 | PTPN1 (0.67) | PTPN1IKBKBBRD4TDO2KDM4E | |
| SCHEMBL2567880 | 0.69 | PTPN1 (1.00) | PTPN1IP6K1HSD17B10ALDH1A1DUSP3 | |
| SCHEMBL18794919 | 0.69 | PTGS2 (0.55) | PTPN1MEN1GAAKMT2AKDM4E | |
| SCHEMBL9185123 | 0.69 | MEN1 (0.50) | ADORA2AIKBKBMEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250002487-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | VENTUS THERAPEUTICS U.S., INC. (US) | 2025-01-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250002487-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | CGAS, TDP1, CYP11B2 | PTPN1 3806/4885ADORA2A 778/4885IKBKB 2616/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.