Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 1.00 |
| ▸ | GAA | P10253 | 1/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | TSHR | P16473 | 5/20 | 0.63 |
| ▸ | POLB | P06746 | 3/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30684542 | 0.98 | KMT2A (0.97) | KMT2AMEN1GAAHSD17B10TSHR | |
| Hydrochloric Acid SCHEMBL30684473 | 0.98 | KMT2A (0.97) | KMT2AMEN1GAAHSD17B10TSHR | |
| SCHEMBL27722453 | 0.86 | KMT2A (0.76) | KMT2AMEN1GAATSHRPOLB | |
| SCHEMBL316093 | 0.86 | KMT2A (0.76) | KMT2AMEN1GAATSHRPOLB | |
| Hydrochloric Acid SCHEMBL4846563 | 0.85 | KMT2A (0.73) | KMT2AMEN1GAATSHRPOLB | |
| SCHEMBL1574735 | 0.85 | KMT2A (0.73) | KMT2AMEN1GAATSHRPOLB | |
| SCHEMBL4718673 | 0.84 | KMT2A (0.72) | KMT2AMEN1GAAHSD17B10TSHR | |
| SCHEMBL10929681 | 0.83 | KMT2A (0.71) | KMT2AMEN1GAATSHRPOLB | |
| SCHEMBL7608812 | 0.83 | KMT2A (0.71) | KMT2AMEN1GAATSHRPOLB | |
| SCHEMBL1260007 | 0.83 | KMT2A (0.71) | KMT2AMEN1GAATSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 129 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1051074-C | Isoxazole-4-carboxamides and hydroxyalkylidenecyanoacetamides pharmaceuticals containing these compounds and their use | HOECHST AG (DE) | 2000-04-05 | — | — | CN | claimed |
| EP-0040494-B1 | CARBAPENAMS AND CARBAPEN-2-EMS AND PROCESS THEREFOR | PFIZER INC. (US) | 1984-02-15 | — | — | EP | claimed |
| US-4429128-A | CARBAPENICILLINS, THIENAMYCINS, BACTERICIDES | PFIZER INC. (US) | 1984-01-31 | — | — | US | claimed |
| US-4407815-A | AMINO ACID DERIVATIVE ANTIBIOTICS | BEECHAM GROUP LIMITED (GB) | 1983-10-04 | — | — | US | claimed |
| US-4348264-A | Photocatalyzed process for producing carbapenams and carbapen-2-ems | PFIZER INC. (US) | 1982-09-07 | — | — | US | claimed |
| EP-0040494-A1 | Carbapenams and carbapen-2-ems and process therefor | PFIZER INC. (US) | 1981-11-25 | — | — | EP | claimed |
| US-3989685-A | FROM PENICILLIN-1-OXIDE | SHINOGI & CO., LTD. (JA) | 1976-11-02 | — | — | US | claimed |
| CN-117279908-A | Heteroaryl compounds for the treatment of cognitive disorders | 加的夫大学学院咨询有限公司 | 2023-12-22 | — | — | CN | disclosed |
| CN-102174031-B | 1,2,3-thiadiazole-1,3,4-thiadiazole compounds and preparation method and application thereof | UNIV NANKAI | 2013-05-08 | — | — | CN | disclosed |
| WO-2012044531-A1 | NOVEL PIPERAZINE ANALOGS WITH SUBSTITUTED HETEROARYL GROUPS AS BROAD-SPECTRUM INFLUENZA ANTIVIRALS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-04-05 | — | — | WO | disclosed |
| CN-102174031-A | 1,2,3-thiadiazole-1,3,4-thiadiazole compounds and preparation method and application thereof | UNIV NANKAI | 2011-09-07 | — | — | CN | disclosed |
| US-7608590-B2 | HCV NS-3 serine protease inhibitors | MEDIVIR AB (SE) | 2009-10-27 | — | — | US | disclosed |
| US-7541368-B2 | 1-(5-tert-butyl-2-p-tolyl-2H-pyrazol-3-yl)-3-{3-[1-(1-methyl-cyclopropanecarbonyl)-piperidin-4-ylmethyl]-phenyl}-urea; use in the treatment of disease states capable of being modulated by the inhibition of p38 kinase and tumor necrosis factor (TNF) | AVENTIS PHARMACEUTICALS INC. (US) | 2009-06-02 | — | — | US | disclosed |
| US-4387051-A | β-Lactam antibiotics, their preparation and their use in pharmaceutical compositions | BEECHAM GROUP LIMITED (GB) | 1983-06-07 | — | — | US | disclosed |
| EP-0073100-A1 | Beta-lactam compounds, their preparation and their use | BEECHAM GROUP PLC (GB) | 1983-03-02 | — | — | EP | disclosed |
| EP-0067518-A1 | Modified beta-lactam compounds | BEECHAM GROUP PLC (GB) | 1982-12-22 | — | — | EP | disclosed |
| US-4348264-A | Photocatalyzed process for producing carbapenams and carbapen-2-ems | PFIZER INC. (US) | 1982-09-07 | — | — | US | disclosed |
| EP-0040494-A1 | Carbapenams and carbapen-2-ems and process therefor | PFIZER INC. (US) | 1981-11-25 | — | — | EP | disclosed |
| EP-0034443-A2 | Beta-lactam antibacterial compounds, their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1981-08-26 | — | — | EP | disclosed |
| EP-0028497-A1 | Beta-lactam antibiotics, their preparation and their use in pharmaceutical compositions | BEECHAM GROUP PLC (GB) | 1981-05-13 | — | — | EP | disclosed |