Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 3/20 | 0.52 |
| ▸ | DPP3 | Q9NY33 | 5/20 | 0.50 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.50 |
| ▸ | CTSB | P07858 | 2/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | F13A1 | P00488 | 2/20 | 0.47 |
| ▸ | TGM2 | P21980 | 2/20 | 0.47 |
| ▸ | TACR1 | P25103 | 2/20 | 0.47 |
| ▸ | NTSR2 | O95665 | 1/20 | 0.46 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.46 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.46 |
| ▸ | REN | P00797 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30511908 | 0.90 | GHSR (0.56) | GHSRDPP3CAPN1CTSBOPRM1 | |
| SCHEMBL30051517 | 0.87 | GHSR (0.53) | GHSRDPP3F13A1TGM2TACR1 | |
| SCHEMBL29812309 | 0.85 | DPP3 (0.64) | GHSRDPP3OPRM1TACR1REN | |
| SCHEMBL2195872 | 0.84 | DPP4 (0.58) | DPP3CAPN1CTSBOPRM1NTSR2 | |
| SCHEMBL30668967 | 0.84 | DPP3 (0.55) | GHSRDPP3CAPN1CTSBTACR1 | |
| SCHEMBL30715835 | 0.83 | TACR1 (0.58) | DPP3OPRM1TACR1 | |
| SCHEMBL28391622 | 0.83 | F13A1 (0.54) | DPP3CAPN1CTSBF13A1TGM2 | |
| SCHEMBL23380930 | 0.83 | GHSR (0.57) | GHSRDPP3OPRM1 | |
| SCHEMBL29534025 | 0.82 | DPP3 (0.53) | GHSRDPP3CAPN1CTSBTACR1 | |
| SCHEMBL29534382 | 0.82 | DPP3 (0.53) | GHSRDPP3CAPN1CTSBTACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190070251-A1 | POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES | NEKTAR THERAPEUTICS | 2019-03-07 | — | — | US | disclosed |
| US-9682153-B2 | Polymer conjugates of therapeutic peptides | NEKTAR THERAPEUTICS (US) | 2017-06-20 | — | — | US | disclosed |
| US-20160022828-A1 | POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES | NEKTAR THERAPEUTICS | 2016-01-28 | — | — | US | disclosed |
| US-20110171312-A1 | MODIFIED THERAPEUTIC PEPTIDES, METHODS OF THEIR PREPARATION AND USE | NEKTAR THERAPEUTICS (US) | 2011-07-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160022828-A1 | POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES | NGLY1, CD44, IAPP | GHSR 1894/4885DPP3 332/4885CAPN1 2889/4885 |
| US-20190070251-A1 | POLYMER CONJUGATES OF THERAPEUTIC PEPTIDES | NGLY1, CD44, IAPP | GHSR 1894/4885DPP3 332/4885CAPN1 2889/4885 |
| US-20110171312-A1 | MODIFIED THERAPEUTIC PEPTIDES, METHODS OF THEIR PREPARATION AND USE | DNPEP, VIP, PTMS | GHSR 1457/4885DPP3 518/4885CAPN1 1090/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.