SCHEMBL30511908

SCHEMBL30511908

O=C(N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N1CCC[C@H]1C(=O)O)[C@@H]1CCCN1

nearest known ligand 0.56

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ GHSR Q92847 4/20 0.56
▸ DPP3 Q9NY33 2/20 0.51
▸ F13A1 P00488 1/20 0.51
▸ TGM2 P21980 1/20 0.51
▸ CYP2C19 P33261 1/20 0.50
▸ CAPN1 P07384 2/20 0.49
▸ CTSB P07858 2/20 0.49
▸ OPRM1 P35372 1/20 0.49
▸ BCHE P06276 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30051517 0.97 GHSR (0.53) GHSRDPP3F13A1TGM2CYP2C19
SCHEMBL2193319 0.90 GHSR (0.52) GHSRDPP3F13A1TGM2CAPN1
SCHEMBL18933365 0.88 DPP3 (0.53) GHSRDPP3F13A1TGM2OPRM1
SCHEMBL14906478 0.88 DPP3 (0.49) GHSRDPP3OPRM1BCHE
SCHEMBL14906600 0.88 DPP3 (0.49) GHSRDPP3OPRM1BCHE
SCHEMBL23380930 0.87 GHSR (0.57) GHSRDPP3OPRM1
SCHEMBL29812309 0.87 DPP3 (0.64) GHSRDPP3OPRM1
SCHEMBL14903326 0.86 DPP3 (0.49) GHSRDPP3OPRM1
SCHEMBL30668967 0.85 DPP3 (0.55) GHSRDPP3CAPN1CTSB
SCHEMBL29533411 0.85 GHSR (0.65) GHSR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4689082-A1 COMPOSITIONS AND METHODS FOR THE TARGETING OF PCSK9 Scribe Therapeutics Inc. (US) 2026-02-11 — — EP disclosed
CN-119019505-B PROTAC polypeptide of targeted ZMYND protein and application thereof 西安交通大学 2025-05-30 — — CN disclosed
CN-117843641-B NSD3 inhibitor and preparation method and application thereof 和径医药科技(上海)有限公司 2025-04-25 — — CN disclosed
WO-2025082409-A1 PURINE COMPOUND AND USE THEREOF 中国科学院上海药物研究所 2025-04-24 — — WO disclosed
WO-2025076000-A2 COMPOSITIONS AND METHODS FOR MODULATING CHROMATIN STATE THE UNIVERSITY OF CHICAGO (US) 2025-04-10 — — WO disclosed
US-20250099405-A1 COMPOSITIONS, METHODS, AND DEVELOPMENT OF ARID4B INHIBITORS UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 2025-03-27 — — US disclosed
WO-2024260445-A1 THIAZOLIDINEDIONE COMPOUND AND PHARMACEUTICAL COMPOSITION AND USE THEREOF 上海科技大学 2024-12-26 — — WO disclosed
CN-119174759-A Thiazolidinedione compound, pharmaceutical composition and application thereof 上海科技大学 2024-12-24 — — CN disclosed
EP-4465977-A2 COMPOSITIONS, METHODS, AND DEVELOPMENT OF ARID4B INHIBITORS University Of Kentucky Research Foundation (US) 2024-11-27 — — EP disclosed
CN-119019505-A PROTAC polypeptide of targeted ZMYND protein and application thereof 西安交通大学 2024-11-26 — — CN disclosed
WO-2024238906-A2 EPIGENETIC REPRESSION PROTEIN THERAPY FOR RASOPATHIES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2024-11-21 — — WO disclosed
WO-2024206555-A1 COMPOSITIONS AND METHODS FOR THE TARGETING OF PCSK9 SCRIBE THERAPEUTICS INC. (US) 2024-10-03 — — WO disclosed
CN-117843641-A NSD3 inhibitor and preparation method and application thereof 和径医药科技(上海)有限公司 2024-04-09 — — CN disclosed
WO-2023141467-A2 COMPOSITIONS, METHODS, AND DEVELOPMENT OF ARID4B INHIBITORS UNIVERSITY OF KENTUCKY RESEARCH FOUNDATION (US) 2023-07-27 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250099405-A1 COMPOSITIONS, METHODS, AND DEVELOPMENT OF ARID4B INHIBITORS ARID2, ACIN1, ATAD2B GHSR 3981/4885DPP3 3782/4885F13A1 3498/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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