Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | STAT1 | P42224 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.57 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.57 |
| ▸ | TUBB | P07437 | 1/20 | 0.57 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.57 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28802494 | 0.87 | TUBB4A (0.63) | SMN1; SMN2MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL30492996 | 0.82 | SMN1; SMN2 (0.68) | SMN1; SMN2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL1851780 | 0.82 | SMN1; SMN2 (0.68) | SMN1; SMN2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL4254443 | 0.82 | GAA (0.48) | SMN1; SMN2MEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL4254437 | 0.82 | GAA (0.48) | SMN1; SMN2MEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL10944710 | 0.82 | SMN1; SMN2 (0.64) | SMN1; SMN2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL7941711 | 0.82 | SMN1; SMN2 (0.64) | SMN1; SMN2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL7941715 | 0.82 | SMN1; SMN2 (0.64) | SMN1; SMN2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL4254439 | 0.80 | CYP19A1 (0.59) | SMN1; SMN2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL21933246 | 0.80 | LMNA (0.59) | SMN1; SMN2MEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10829466-B2 | Stilbene derivative and preparation method thereof | BEIJING INSTITUTE OF TECHNOLOGY (CN) | 2020-11-10 | — | — | US | disclosed |
| US-20200148662-A1 | NOVEL STILBENE DERIVATIVE AND PREPARATION METHOD THEREOF | BEIJING INSTITUTE OF TECHNOLOGY (CN) | 2020-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10829466-B2 | Stilbene derivative and preparation method thereof | STS, F12, GLB1 | SMN1; SMN2 3805/4885MEN1 1417/4885KMT2A 3011/4885 |
| US-20200148662-A1 | NOVEL STILBENE DERIVATIVE AND PREPARATION METHOD THEREOF | STS, F12, STK38L | SMN1; SMN2 3934/4885MEN1 1334/4885KMT2A 3156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.