Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB4A | P04350 | 5/20 | 0.68 |
| ▸ | TUBB | P07437 | 5/20 | 0.68 |
| ▸ | TUBA3C | P0DPH7 | 5/20 | 0.68 |
| ▸ | TUBA1B | P68363 | 5/20 | 0.68 |
| ▸ | TUBA4A | P68366 | 5/20 | 0.68 |
| ▸ | TUBB4B | P68371 | 5/20 | 0.68 |
| ▸ | TUBB3 | Q13509 | 5/20 | 0.68 |
| ▸ | TUBB2A | Q13885 | 5/20 | 0.68 |
| ▸ | TUBB8 | Q3ZCM7 | 5/20 | 0.68 |
| ▸ | TUBA3E | Q6PEY2 | 5/20 | 0.68 |
| ▸ | TUBA1A | Q71U36 | 5/20 | 0.68 |
| ▸ | TUBA1C | Q9BQE3 | 5/20 | 0.68 |
| ▸ | TUBB6 | Q9BUF5 | 5/20 | 0.68 |
| ▸ | TUBB2B | Q9BVA1 | 5/20 | 0.68 |
| ▸ | TUBB1 | Q9H4B7 | 5/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL69858 | 0.91 | TUBB4A (0.79) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL31527836 | 0.86 | TUBB1 (0.68) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL27182693 | 0.86 | TUBB1 (0.68) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL27183379 | 0.86 | TUBB4A (0.68) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL29442255 | 0.84 | TUBB4A (0.75) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL15042812 | 0.84 | TUBB4A (0.75) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL29066052 | 0.81 | TUBB1 (1.00) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL27704501 | 0.80 | AKR1B1 (0.53) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL18354819 | 0.80 | HTT (0.51) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL8794626 | 0.79 | TUBB4A (0.51) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220002232-A1 | PROCESS FOR THE PREPARATION OF 4,5-DIHYDROXY-2-(4-METHYLBENZYL)ISOPHTHALONITRILE | ORION CORPORATION (FI) | 2022-01-06 | — | — | US | claimed |
| EP-3877360-A1 | PROCESS FOR THE PREPARATION OF 4,5-DIHYDROXY-2-(4-METHYLBENZYL)ISOPHTHALONITRILE | Orion Corporation (FI) | 2021-09-15 | — | — | EP | claimed |
| CN-113166042-A | Method for preparing 4, 5-dihydroxy-2- (4-methylbenzyl) isophthalonitrile | 奥赖恩公司 | 2021-07-23 | — | — | CN | claimed |
| US-20220002232-A1 | PROCESS FOR THE PREPARATION OF 4,5-DIHYDROXY-2-(4-METHYLBENZYL)ISOPHTHALONITRILE | ORION CORPORATION (FI) | 2022-01-06 | — | — | US | disclosed |
| US-20220002232-A1 | PROCESS FOR THE PREPARATION OF 4,5-DIHYDROXY-2-(4-METHYLBENZYL)ISOPHTHALONITRILE | ORION CORPORATION (FI) | 2022-01-06 | — | — | US | disclosed |
| US-20220002232-A1 | PROCESS FOR THE PREPARATION OF 4,5-DIHYDROXY-2-(4-METHYLBENZYL)ISOPHTHALONITRILE | ORION CORPORATION (FI) | 2022-01-06 | — | — | US | disclosed |
| EP-3877360-A1 | PROCESS FOR THE PREPARATION OF 4,5-DIHYDROXY-2-(4-METHYLBENZYL)ISOPHTHALONITRILE | Orion Corporation (FI) | 2021-09-15 | — | — | EP | disclosed |
| EP-3877360-A1 | PROCESS FOR THE PREPARATION OF 4,5-DIHYDROXY-2-(4-METHYLBENZYL)ISOPHTHALONITRILE | Orion Corporation (FI) | 2021-09-15 | — | — | EP | disclosed |
| CN-113166042-A | Method for preparing 4, 5-dihydroxy-2- (4-methylbenzyl) isophthalonitrile | 奥赖恩公司 | 2021-07-23 | — | — | CN | disclosed |
| CN-113166042-A | Method for preparing 4, 5-dihydroxy-2- (4-methylbenzyl) isophthalonitrile | 奥赖恩公司 | 2021-07-23 | — | — | CN | disclosed |
| WO-2020094928-A1 | PROCESS FOR THE PREPARATION OF 4,5-DIHYDROXY-2-(4-METHYLBENZYL)ISOPHTHALONITRILE | ORION CORPORATION (FI) | 2020-05-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220002232-A1 | PROCESS FOR THE PREPARATION OF 4,5-DIHYDROXY-2-(4-METHYLBENZYL)ISOPHTHALONITRILE | COMT, DDT, HPD | TUBB4A 924/4885TUBB 2319/4885TUBA3C 1848/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.