Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | AKT1 | P31749 | 1/20 | 0.39 |
| ▸ | AKT2 | P31751 | 1/20 | 0.39 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28555999 | 0.86 | NPC1 (0.38) | ALDH1A1AKT1AKT2HDAC1NPC1 | |
| SCHEMBL21936047 | 0.82 | KDM4E (0.43) | ALDH1A1KDM4EHSD17B10SMN1; SMN2AKT1 | |
| SCHEMBL21936043 | 0.82 | KDM4E (0.43) | ALDH1A1KDM4EHSD17B10SMN1; SMN2AKT1 | |
| SCHEMBL17434496 | 0.80 | HDAC1 (0.44) | ALDH1A1KDM4EHSD17B10SMN1; SMN2AKT1 | |
| SCHEMBL21936037 | 0.76 | HDAC1 (0.34) | HDAC1POLB | |
| SCHEMBL21936499 | 0.75 | MRGPRX4 (0.36) | ALDH1A1KDM4EHSD17B10SMN1; SMN2AKT1 | |
| SCHEMBL31091944 | 0.75 | AKT1 (0.43) | ALDH1A1KDM4EHSD17B10SMN1; SMN2AKT1 | |
| SCHEMBL27272953 | 0.72 | GRM2 (0.48) | ALDH1A1KDM4EHSD17B10SMN1; SMN2AKT1 | |
| SCHEMBL976070 | 0.72 | KDM4E (0.48) | ALDH1A1KDM4EHSD17B10SMN1; SMN2AKT1 | |
| SCHEMBL24997460 | 0.71 | ALDH1A1 (0.41) | ALDH1A1KDM4EHSD17B10SMN1; SMN2AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112601745-B | Azaaryl amide derivative and preparation method and application thereof | 上海和誉生物医药科技有限公司 | 2023-06-27 | — | — | CN | disclosed |
| WO-2020082921-A1 | NITROGEN HETEROARYL AMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 上海和誉生物医药科技有限公司 | 2020-04-30 | — | — | WO | disclosed |