Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 17/20 | 0.34 |
| ▸ | AHR | P35869 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21936050 | 0.80 | KDM4E (0.38) | AHRPOLBMAPTRECQL | |
| SCHEMBL28555999 | 0.79 | NPC1 (0.38) | HDAC1POLBRECQL | |
| SCHEMBL23726410 | 0.77 | ALDH1A1 (0.33) | AHRMAPT | |
| SCHEMBL13144230 | 0.77 | ALDH1A1 (0.44) | MAPT | |
| SCHEMBL21936310 | 0.77 | PTGDR2 (0.38) | HDAC1PTGDR2 | |
| SCHEMBL21937177 | 0.77 | AHR (0.31) | AHR | |
| SCHEMBL21936038 | 0.76 | ALDH1A1 (0.41) | HDAC1POLB | |
| SCHEMBL31528577 | 0.75 | RAB9A (0.49) | POLBMAPT | |
| SCHEMBL21936039 | 0.75 | HDAC1 (0.37) | HDAC1AHRPTGDR2 | |
| SCHEMBL29070052 | 0.73 | ALDH1A1 (0.43) | POLBMAPTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112601745-B | Azaaryl amide derivative and preparation method and application thereof | 上海和誉生物医药科技有限公司 | 2023-06-27 | — | — | CN | disclosed |
| CN-112601745-A | Azaaryl amide derivative and preparation method and application thereof | 上海和誉生物医药科技有限公司 | 2021-04-02 | — | — | CN | disclosed |
| WO-2020082921-A1 | NITROGEN HETEROARYL AMIDE DERIVATIVE, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF | 上海和誉生物医药科技有限公司 | 2020-04-30 | — | — | WO | disclosed |