Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 7/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 4/20 | 0.30 |
| ▸ | HTR2C | P28335 | 4/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18911813 | 0.89 | KDM1A (0.37) | KDM1A | |
| SCHEMBL25687462 | 0.89 | HTR7 (0.31) | HTR7 | |
| SCHEMBL21872486 | 0.85 | — | — | |
| SCHEMBL25687546 | 0.85 | KDM1A (0.33) | KDM1A | |
| SCHEMBL24901130 | 0.80 | HTR2A (0.33) | HTR2AHTR2C | |
| SCHEMBL21872485 | 0.76 | KDM4E (0.38) | HTR2AHTR2C | |
| SCHEMBL21872476 | 0.73 | HTR2C (0.46) | KDM1AHTR7HTR2AHTR2C | |
| SCHEMBL24144917 | 0.73 | HTR7 (0.36) | HTR7HTR2AHTR2C | |
| SCHEMBL18876145 | 0.73 | CDK4 (0.38) | — | |
| SCHEMBL20512635 | 0.72 | KDM1A (0.37) | KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3633380-A1 | METHOD FOR PREDICTING THERAPEUTIC EFFECT OF LSD1 INHIBITOR BASED ON EXPRESSION OF INSM1 | Taiho Pharmaceutical Co., Ltd. (JP) | 2020-04-08 | — | — | EP | disclosed |