SCHEMBL21936342

SCHEMBL21936342

C[SiH](C)c1ccccc1[SiH](C)C

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.35
ACHE P22303 2/20 0.35
ALOX12 P18054 2/20 0.33
LMNA P02545 1/20 0.33
ALDH1A1 P00352 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
CYP2A6 P11509 1/20 0.31
CYP1A2 P05177 1/20 0.30
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA4 P22748 1/20 0.30
CA7 P43166 1/20 0.30
CA9 Q16790 1/20 0.30
CA14 Q9ULX7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL148575 1.00 TSHR (0.35) TSHRACHEALOX12LMNAALDH1A1
SCHEMBL21722357 0.83 MEN1 (0.33) TSHRACHELMNAALDH1A1TDP1
SCHEMBL3150402 0.81 TSHR (0.50) TSHRACHEALOX12LMNAALDH1A1
SCHEMBL3854842 0.78 ALDH1A1 (0.43) ALDH1A1TDP1CA1CA2CA4
SCHEMBL3145784 0.78 ACHE (0.43) ACHEALDH1A1
SCHEMBL561054 0.78
SCHEMBL4363270 0.78 ALDH1A1 (0.47) TSHRLMNAALDH1A1TDP1CYP1A2
SCHEMBL1037186 0.78 TSHR (0.47) TSHRLMNAALDH1A1CYP2A6CYP1A2
SCHEMBL17728183 0.78
SCHEMBL3915810 0.78 CYP3A4 (0.47) TSHRALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118955550-A Bio-based intrinsic high-heat-conductivity insulating epoxy resin, cured product, preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2024-11-15 CN claimed
CN-115244088-A Substituted silanes as chain transfer agents for polyolefin production 陶氏环球技术有限责任公司 2022-10-25 CN claimed
CN-113226473-B KIF18A inhibitors 美国安进公司 2025-05-13 CN disclosed
EP-4482889-A1 (METH)ACRYLATED HYPERBRANCHED POLYMERS, METHOD OF MAKING, COMPOSITIONS INCLUDING THE SAME, AND ELECTRONIC DEVICE 3M Innovative Properties Company (US) 2025-01-01 EP disclosed
CN-119095856-A Novel anion receptor compound and electrolyte comprising the same 自人新能有限公司 2024-12-06 CN disclosed
CN-118955550-A Bio-based intrinsic high-heat-conductivity insulating epoxy resin, cured product, preparation method and application thereof 中国科学院宁波材料技术与工程研究所 2024-11-15 CN disclosed
CN-118696079-A (Meth) acrylated hyperbranched polymer, preparation method thereof, composition comprising same and electronic device 3M创新有限公司 2024-09-24 CN disclosed
CN-115244088-B Substituted silanes as chain transfer agents for polyolefin production 陶氏环球技术有限责任公司 2024-09-20 CN disclosed
CN-115244088-B Substituted silanes as chain transfer agents for polyolefin production 陶氏环球技术有限责任公司 2024-09-20 CN disclosed
CN-117887082-A Resin containing phenylene bis- (dimethylhydroxysilicon) structure for external heat-resistant coating of aircraft and preparation method of resin 中昊北方涂料工业研究设计院有限公司 2024-04-16 CN disclosed
WO-2023161753-A1 (METH)ACRYLATED HYPERBRANCHED POLYMERS, METHOD OF MAKING, COMPOSITIONS INCLUDING THE SAME, AND ELECTRONIC DEVICE 3M INNOVATIVE PROPERTIES COMPANY (US) 2023-08-31 WO disclosed
CN-115244088-A Substituted silanes as chain transfer agents for polyolefin production 陶氏环球技术有限责任公司 2022-10-25 CN disclosed
CN-110366449-B Catalyst for hydrosilylation, hydrogenation, and hydrosilane reduction 国立大学法人九州大学 2022-10-21 CN disclosed
WO-2022093448-A1 THERMOPLASTIC VULCANIZATE COMPOSITIONS AND ARTICLES CONTAINING THE SAME CELANESE INTERNATIONAL CORPORATION (US) 2022-05-05 WO disclosed
CN-114391012-A Pyridine derivatives as KIF18A inhibitors 美国安进公司 2022-04-22 CN disclosed
CN-114302880-A KIF18A inhibitors 美国安进公司 2022-04-08 CN disclosed
CN-114269731-A KIF18A inhibitors 美国安进公司 2022-04-01 CN disclosed
CN-110229524-B Curable silicone composition for light-reflecting material, cured silicone resin, reflector, and LED device 信越化学工业株式会社 2022-03-29 CN disclosed
CN-114133574-A Bridged naphthene toughened silicone resin and preparation method thereof 山东省科学院新材料研究所 2022-03-04 CN disclosed
EP-3269724-B1 MONONUCLEAR IRON COMPLEX AND ORGANIC SYNTHESIS REACTION USING SAME UNIV KYUSHU NAT UNIV CORP (JP) 2020-04-22 EP disclosed