Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13062152 | 0.92 | EPHX1 (0.42) | EPHX1PAOXHTR2AHRH1LMNA | |
| SCHEMBL14525183 | 0.92 | EPHX1 (0.42) | EPHX1PAOXHTR2AHRH1LMNA | |
| SCHEMBL3071603 | 0.84 | — | — | |
| SCHEMBL18756769 | 0.82 | LMNA (0.32) | EPHX1LMNACNR1ADRA1ATDP1 | |
| SCHEMBL21557 | 0.82 | EPHX1 (0.42) | EPHX1LMNA | |
| SCHEMBL23914444 | 0.81 | EPHX1 (0.54) | EPHX1HTR2AHRH1SIGMAR1 | |
| SCHEMBL19450330 | 0.81 | POLB (0.31) | — | |
| SCHEMBL18828149 | 0.80 | LMNA (0.42) | LMNASLC6A4 | |
| SCHEMBL10700618 | 0.80 | EPHX1 (0.46) | EPHX1LMNA | |
| SCHEMBL20840762 | 0.80 | EPHX1 (0.46) | EPHX1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3633380-A1 | METHOD FOR PREDICTING THERAPEUTIC EFFECT OF LSD1 INHIBITOR BASED ON EXPRESSION OF INSM1 | Taiho Pharmaceutical Co., Ltd. (JP) | 2020-04-08 | — | — | EP | disclosed |