⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14525183 | 0.86 | EPHX1 (0.42) | — | |
| SCHEMBL13062152 | 0.86 | EPHX1 (0.42) | — | |
| SCHEMBL21936360 | 0.84 | EPHX1 (0.46) | — | |
| SCHEMBL19445841 | 0.82 | SLC6A4 (0.37) | — | |
| SCHEMBL28117588 | 0.81 | EPHX1 (0.36) | — | |
| SCHEMBL12855699 | 0.78 | — | — | |
| SCHEMBL7936451 | 0.78 | — | — | |
| SCHEMBL23690762 | 0.77 | LMNA (0.36) | — | |
| SCHEMBL4162488 | 0.77 | — | — | |
| SCHEMBL15714300 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024019995-A1 | QUINOXALINEDIONE AND PYRIDO [2, 3-B]PYRAZINE-2, 3-DIONE B CELL LYMPHOMA 6 (BCL6) DEGRADERS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2024-01-25 | — | — | WO | disclosed |
| WO-2023086432-A1 | PRODRUGS OF NEUROSTEROID ANALOGS AND USES THEREOF | EMORY UNIVERSITY (US) | 2023-05-19 | — | — | WO | disclosed |
| EP-4180427-A1 | COMPOUND CAPABLE OF INHIBITING AND DEGRADING ANDROGEN RECEPTORS, AND PHARMACEUTICAL COMPOSITIONS AND PHARMACEUTICAL USES THEREOF | Sichuan Haisco Pharmaceutical Co., Ltd. (CN) | 2023-05-17 | — | — | EP | disclosed |
| CN-110787720-B | Fluorine-containing gemini surfactant and preparation method thereof | 济南齐氟新材料技术有限公司 | 2023-04-25 | — | — | CN | disclosed |
| WO-2022112345-A1 | ARYL DERIVATIVES FOR TREATING TRPM3 MEDIATED DISORDERS | KATHOLIEKE UNIVERSITEIT LEUVEN (BE) | 2022-06-02 | — | — | WO | disclosed |
| EP-2235022-B1 | DIMERIC DERIVATIVES OF ARTEMISININ AND APPLICATION IN ANTICANCER THERAPY | PF MEDICAMENT (FR) | 2015-08-05 | — | — | EP | disclosed |
| US-8236850-B2 | Dimeric derivatives of artemisinin and application in anticancer therapy | PIERRE FABRE MEDICAMENT (FR) | 2012-08-07 | — | — | US | disclosed |
| US-7905928-B2 | Reactive dyes, processes for their preparation and their use | HUNTSMAN INTERNATIONAL LLC (US) | 2011-03-15 | — | — | US | disclosed |
| US-20100266570-A1 | DIMERIC DERIVATIVES OF ARTEMISININ AND APPLICATION IN ANTICANCER THERAPY | PIERRE FABRE MEDICAMENT (FR) | 2010-10-21 | — | — | US | disclosed |
| US-20100251490-A1 | REACTIVE DYES, PROCESSES FOR THEIR PREPARATION AND THEIR USE | HUNTSMAN INTERNATIONAL LLC (US) | 2010-10-07 | — | — | US | disclosed |
| US-20020099167-A1 | Asymmetric disulfide compounds, method for producing the same, and optical products | HOYA CORPORATION | 2002-07-25 | — | — | US | disclosed |