Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.33 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.33 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.33 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19157350 | 0.80 | APP (0.34) | APPALDH1A1CYP3A4RECQLHSD17B10 | |
| SCHEMBL24080716 | 0.74 | MAPK13 (0.44) | ALDH1A1CYP3A4RECQLHSD17B10THRB | |
| SCHEMBL13271458 | 0.74 | TPMT (0.39) | APPCYP3A4HSD17B10TP53ALOX15 | |
| SCHEMBL21935796 | 0.74 | CYP19A1 (0.41) | APPALDH1A1CYP3A4HSD17B10THRB | |
| SCHEMBL18460837 | 0.73 | ATM (0.38) | ALDH1A1CYP3A4RECQLHPGDTSHR | |
| SCHEMBL28085607 | 0.73 | ATM (0.38) | ALDH1A1CYP3A4RECQLHPGDTSHR | |
| SCHEMBL11703026 | 0.73 | APP (0.45) | APPALDH1A1CYP3A4RECQLHSD17B10 | |
| SCHEMBL25099709 | 0.72 | LMNA (0.41) | ALDH1A1KCNH2RAB9A | |
| SCHEMBL19346389 | 0.71 | APP (0.43) | APPALDH1A1CYP3A4RECQLHSD17B10 | |
| SCHEMBL20628632 | 0.71 | MAPK13 (0.38) | ALDH1A1HSD17B10HPGDALOX15TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2999699-B1 | PURINE DIONES AS WNT PATHWAY MODULATORS | AGENCY SCIENCE TECH & RES (SG) | 2020-04-29 | — | — | EP | disclosed |