Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 9/20 | 0.48 |
| ▸ | HTR2A | P28223 | 8/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 2/20 | 0.33 |
| ▸ | KRAS | P01116 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21936470 | 0.84 | HTR2C (0.44) | HTR2CHTR2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL21872466 | 0.81 | HTR2C (0.54) | HTR2CHTR2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL18911877 | 0.79 | HTR2C (0.53) | HTR2CHTR2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL21872476 | 0.78 | HTR2C (0.46) | HTR2CHTR2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL21872463 | 0.77 | HTR2C (0.43) | HTR2CHTR2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL18912167 | 0.77 | GRIN2B (0.52) | HTR2CHTR2AKMT2AGRIN2B | |
| SCHEMBL25689136 | 0.76 | HTR2C (0.65) | HTR2CHTR2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL21872574 | 0.76 | HTR2C (0.45) | HTR2CHTR2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL21872944 | 0.76 | HTR2C (0.46) | HTR2CHTR2ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL25010274 | 0.76 | HTR2A (0.55) | HTR2CHTR2AKMT2ASLC2A1EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3633380-A1 | METHOD FOR PREDICTING THERAPEUTIC EFFECT OF LSD1 INHIBITOR BASED ON EXPRESSION OF INSM1 | Taiho Pharmaceutical Co., Ltd. (JP) | 2020-04-08 | — | — | EP | disclosed |