SCHEMBL21937059

SCHEMBL21937059

CCC(=O)N[C@@H](CCC(=O)N[C@@H](CCC(=O)NCCCC[C@H](NC)C(C)=O)C(=O)O)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 1/20 0.49
▸ NOD1 Q9Y239 7/20 0.49
▸ GLP1R P43220 8/20 0.48
▸ ALB P02768 2/20 0.45
▸ EPHX2 P34913 1/20 0.43
▸ MMP2 P08253 1/20 0.40
▸ MMP9 P14780 1/20 0.40
▸ MMP8 P22894 1/20 0.40
▸ MMP12 P39900 1/20 0.40
▸ MMP14 P50281 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14118103 0.92 NOD1 (0.50) FOLH1NOD1GLP1RALBEPHX2
SCHEMBL24796107 0.89 NOD1 (0.66) NOD1GLP1REPHX2
SCHEMBL14852205 0.89 NOD1 (0.66) NOD1GLP1REPHX2
SCHEMBL7894607 0.89 NOD1 (0.66) NOD1GLP1REPHX2
SCHEMBL26190934 0.89 NOD1 (0.66) NOD1GLP1REPHX2
SCHEMBL18710730 0.88 ALB (0.56) FOLH1NOD1GLP1RALB
SCHEMBL24558585 0.88 GLP1R (0.54) FOLH1NOD1GLP1RALBEPHX2
SCHEMBL21242702 0.88 GLP1R (0.54) FOLH1NOD1GLP1RALBEPHX2
SCHEMBL24558475 0.88 GLP1R (0.54) FOLH1NOD1GLP1RALBEPHX2
SCHEMBL21938093 0.88 GLP1R (0.54) FOLH1NOD1GLP1RALBEPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10604555-B2 GIP derivatives and uses thereof NOVO NORDISK A/S (DK) 2020-03-31 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10604555-B2 GIP derivatives and uses thereof GIPR, GLP1R, GPR119 FOLH1 327/4885NOD1 2846/4885GLP1R 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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