Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 2/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | WDR5 | P61964 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 8/20 | 0.34 |
| ▸ | HTR7 | P34969 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | DHODH | Q02127 | 2/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.30 |
| ▸ | F10 | P00742 | 1/20 | 0.30 |
| ▸ | PLG | P00747 | 1/20 | 0.30 |
| ▸ | PLAU | P00749 | 1/20 | 0.30 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.30 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17233969 | 0.89 | PDK2 (0.38) | PRSS1PRSS2PRSS3PDK2HTR7 | |
| SCHEMBL24742667 | 0.88 | PDK2 (0.44) | PRSS1PRSS2PRSS3WDR5PDK2 | |
| SCHEMBL23018864 | 0.83 | PDK2 (0.33) | PDK2HTR7HTR2BDHODH | |
| SCHEMBL12697697 | 0.81 | PDK2 (0.32) | PDK2HTR7HTR2BDHODH | |
| SCHEMBL22238814 | 0.81 | PDK2 (0.35) | PDK2 | |
| SCHEMBL22930624 | 0.81 | WDR5 (0.39) | PRSS1PRSS2PRSS3WDR5PDK2 | |
| SCHEMBL21845658 | 0.80 | PRSS1 (0.50) | PRSS1PRSS2PRSS3WDR5DHODH | |
| SCHEMBL17345759 | 0.78 | WDR5 (0.39) | PRSS1PRSS2PRSS3WDR5PDK2 | |
| SCHEMBL20405391 | 0.77 | PDK2 (0.36) | PRSS1PRSS2PRSS3PDK2F10 | |
| SCHEMBL20204500 | 0.76 | PDK2 (0.36) | PDK2HTR7HTR2BF2F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020064662-A2 | METHOD FOR PRODUCING STERICALLY HINDERED, NITROGEN-CONTAINING HETEROAROMATIC COMPOUNDS | MERCK PATENT GMBH (DE) | 2020-04-02 | — | — | WO | disclosed |