Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18508820 | 0.84 | TP53 (0.50) | TP53THRBKDM4EALDH1A1 | |
| SCHEMBL16727200 | 0.82 | TP53 (0.42) | TP53THRBKDM4EALDH1A1 | |
| SCHEMBL16727214 | 0.79 | TP53 (0.42) | TP53THRBKDM4EALDH1A1 | |
| SCHEMBL16727202 | 0.78 | TP53 (0.40) | TP53THRBKDM4EALDH1A1 | |
| SCHEMBL16727189 | 0.78 | TP53 (0.40) | TP53THRBKDM4EALDH1A1 | |
| SCHEMBL20274232 | 0.77 | PARP1 (0.38) | — | |
| SCHEMBL16728930 | 0.75 | TP53 (0.38) | TP53THRB | |
| SCHEMBL16708694 | 0.73 | MAP3K5 (0.34) | TP53ATAD2KDM4EALDH1A1 | |
| SCHEMBL16727204 | 0.73 | DRD2 (0.41) | TP53THRB | |
| SCHEMBL16729585 | 0.71 | TP53 (0.38) | TP53THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3633380-A1 | METHOD FOR PREDICTING THERAPEUTIC EFFECT OF LSD1 INHIBITOR BASED ON EXPRESSION OF INSM1 | Taiho Pharmaceutical Co., Ltd. (JP) | 2020-04-08 | — | — | EP | disclosed |