Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 2/20 | 0.35 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16729585 | 0.81 | TP53 (0.38) | ARMAP3K5 | |
| SCHEMBL4790802 | 0.80 | ALOX15 (0.35) | ARMAP3K5 | |
| SCHEMBL1494121 | 0.80 | ALOX15 (0.35) | ARMAP3K5 | |
| SCHEMBL16728930 | 0.78 | TP53 (0.38) | ARMAP3K5 | |
| SCHEMBL1494430 | 0.78 | HTR2A (0.40) | — | |
| SCHEMBL21937331 | 0.77 | TP53 (0.40) | — | |
| SCHEMBL18712138 | 0.71 | S1PR1 (0.36) | — | |
| SCHEMBL1494362 | 0.71 | P2RX3 (0.41) | — | |
| SCHEMBL30215798 | 0.71 | P2RX3 (0.41) | — | |
| SCHEMBL16708694 | 0.69 | MAP3K5 (0.34) | MAP3K5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2922845-B1 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | MERIAL INC (US) | 2018-06-20 | — | — | EP | disclosed |