Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 4/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | USP8 | P40818 | 1/20 | 0.37 |
| ▸ | USP7 | Q93009 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | BCL2 | P10415 | 1/20 | 0.34 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.33 |
| ▸ | ILF3 | Q12906 | 1/20 | 0.33 |
| ▸ | GAPDH | P04406 | 1/20 | 0.33 |
| ▸ | PTPRC | P08575 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21938640 | 0.85 | MAPT (0.40) | MAPTPKMALDH1A1GAAEGFR | |
| SCHEMBL29963182 | 0.81 | MAPT (0.48) | MAPTPKMALDH1A1GAAEGFR | |
| SCHEMBL22109491 | 0.80 | MAPT (0.42) | MAPTPKMALDH1A1GAAEGFR | |
| SCHEMBL31415099 | 0.79 | MAPT (0.35) | MAPTPKMALDH1A1GAAEGFR | |
| SCHEMBL470766 | 0.78 | ALDH1A1 (0.38) | MAPTPKMALDH1A1GAAEGFR | |
| SCHEMBL22109492 | 0.78 | MAPT (0.35) | MAPTPKMALDH1A1GAAEGFR | |
| SCHEMBL25747893 | 0.78 | MAPT (0.35) | MAPTPKMALDH1A1GAAEGFR | |
| SCHEMBL22109212 | 0.77 | ALDH1A1 (0.34) | MAPTPKMALDH1A1GAAEGFR | |
| SCHEMBL21938950 | 0.73 | DNMT1 (0.56) | MAPTPKMALDH1A1GAACA1 | |
| SCHEMBL19230417 | 0.73 | ALDH1A1 (0.52) | MAPTALDH1A1GAAMCL1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020052194-A1 | FUSED RING BENZOTHIADIAZOLE-BASED NON-FULLERENE ACCEPTOR MATERIAL, PREPARATION METHOD THEREFOR AND USE THEREOF | 中南大学 | 2020-03-19 | — | — | WO | disclosed |