SCHEMBL219400

SCHEMBL219400

[CH2]CN1CCNC1=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1446059 0.86
SCHEMBL666368 0.81
SCHEMBL10968482 0.79 POLB (0.35)
SCHEMBL13236669 0.79 ALDH1A1 (0.50)
SCHEMBL4037683 0.79 ALDH1A1 (0.50)
SCHEMBL166418 0.76
SCHEMBL360815 0.76
SCHEMBL10512933 0.75
SCHEMBL13843636 0.75 ALDH1A1 (0.47)
SCHEMBL17599192 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 774 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4399206-A1 PAPD5 AND/OR PAPD7 INHIBITING 4-OXO-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID DERIVATIVES Redona Therapeutics, Inc. (US) 2024-07-17 EP claimed
CN-118201914-A 4-Oxo-1, 4-dihydroquinoline-3-carboxylic acid derivatives as PAPD5 and/or PAPD7 inhibitors 雷多纳治疗公司 2024-06-14 CN claimed
US-11802173-B2 Voided latex particles containing functionalized outer shells ARKEMA INC. (US) 2023-10-31 US claimed
EP-3519471-B1 AQUEOUS POLYMER DISPERSION AND USE THEREOF AS INK ANCHORAGE PRIMER BASF SE (DE) 2023-06-21 EP claimed
WO-2023039089-A1 PAPD5 AND/OR PAPD7 INHIBITING 4-OXO-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID DERIVATIVES TWENTYEIGHT-SEVEN, INC. (US) 2023-03-16 WO claimed
US-20220098349-A1 VOIDED LATEX PARTICLES CONTAINING FUNCTIONALIZED OUTER SHELLS ARKEMA INC (US) 2022-03-31 US claimed
US-11161990-B2 Voided latex particles containing functionalized outer shells ARKEMA INC. (US) 2021-11-02 US claimed
CN-108174603-B 1-heteroaryl-indoline-4-carboxamides as GPR52 modulators 阿芮纳制药有限公司 2021-07-02 CN claimed
CN-107848248-B Cavitated latex particles with functionalized shell 阿科玛股份有限公司 2021-04-27 CN claimed
US-10597477-B2 Finely divided aqueous emulsion polymers and use thereof for hydrophobic coatings BASF SE (DE) 2020-03-24 US claimed
US-20020094974-A1 Compounds specific to adenosine A3 receptor and uses thereof OSI PHARMACEUTICALS, INC. 2002-07-18 US claimed
EP-1216243-A1 QUINAZOLINONES AND ANALOGUES AND THEIR USE AS LOCAL ANESTHETICS Advanced Medicine, Inc. (US) 2002-06-26 EP claimed
WO-2001039777-A1 COMPOUNDS SPECIFIC TO ADENOSINE A1 A2A, AND A3 RECEPTORS AND USES THEREOF OSI PHARMACEUTICALS, INC. (US) 2001-06-07 WO claimed
WO-2001025234-A1 QUINAZOLINONES AND ANALOGUES AND THEIR USE AS LOCAL ANESTHETICS ADVANCED MEDICINE, INC. (US) 2001-04-12 WO claimed
EP-0533824-B1 PIPERIDYL-SUBSTITUTED INDOLES LUNDBECK & CO AS H (DK) 1994-11-09 EP claimed
EP-0533824-A1 PIPERIDYL-SUBSTITUTED INDOLES. LUNDBECK & CO AS H (DK) 1993-03-31 EP claimed
WO-1992000070-A1 PIPERIDYL-SUBSTITUTED INDOLES H. LUNDBECK A/S (DK) 1992-01-09 WO claimed
EP-0131374-B1 PROCESS AND INTERMEDIATES FOR THE PREPARATION OF PENEM DERIVATIVES PFIZER INC. (US) 1988-11-23 EP claimed
US-4619783-A BACTERICIDES PFIZER INC. (US) 1986-10-28 US claimed
EP-0131374-A1 Process and intermediates for the preparation of penem derivatives PFIZER INC. (US) 1985-01-16 EP claimed