SCHEMBL4037683

SCHEMBL4037683

O=C1NCCN1CN1CCNC1=O

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.50
POLB P06746 3/20 0.50
KMT2A Q03164 3/20 0.46
MAPT P10636 3/20 0.46
CYP2C9 P11712 2/20 0.46
CYP2C19 P33261 2/20 0.46
MEN1 O00255 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
KDM4E B2RXH2 2/20 0.46
CYP1A2 P05177 1/20 0.46
CYP3A4 P08684 1/20 0.46
CYP2D6 P10635 1/20 0.46
PER2 O15055 1/20 0.39
RAB9A P51151 1/20 0.38
RET P07949 1/20 0.37
KDR P35968 1/20 0.37
LMNA P02545 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14426089 0.87 ALDH1A1 (0.46) ALDH1A1POLBKMT2AMAPTCYP2C9
SCHEMBL13236669 0.83 ALDH1A1 (0.50) ALDH1A1POLBKMT2AMAPTCYP2C9
SCHEMBL13843635 0.80 ALDH1A1 (0.38) ALDH1A1POLBKMT2AMAPTCYP2C9
SCHEMBL15698626 0.79
SCHEMBL17599192 0.79
SCHEMBL301524 0.79
SCHEMBL13843636 0.79 ALDH1A1 (0.47) ALDH1A1POLBKMT2AMAPTCYP2C9
SCHEMBL10512933 0.79
SCHEMBL219400 0.79
SCHEMBL8741734 0.79

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7560266-B2 Method to enhance biodegradation of sulfonated aliphatic-aromatic co-polyesters by addition of a microbial consortium E. I. DU PONT DE NEMOURS AND COMPANY (US) 2009-07-14 US disclosed
US-7528200-B2 Epoxy hardener systems based on aminobis(methylene-ethyleneurea) ARDES ENTERPRISES, INC. (US) 2009-05-05 US disclosed
US-20070179257-A1 Epoxy hardener systems based on aminomethylene-ethyleneureas ARDES ENTERPRISES, INC. 2007-08-02 US disclosed
WO-2006084261-A2 METHOD TO ENHANCE BIODEGRADATION OF SULFONATED ALIPHATIC-AROMATIC CO-POLYESTERS BY ADDITION OF A MICROBIAL CONSORTIUM E.I. DUPONT DE NEMOURS AND COMPANY (US) 2006-08-10 WO disclosed
US-20060177930-A1 Method to enhance biodegradation of sulfonated aliphatic-aromatic co-polyesters by addition of a microbial consortium E. I. DU PONT DE NEMOURS AND COMPANY 2006-08-10 US disclosed
US-7053130-B2 Method to accelerate biodegradation of aliphatic-aromatic co-polyesters by enzymatic treatment E. I . DU PONT DE NEMOURS AND COMPANY (US) 2006-05-30 US disclosed
WO-2005118693-A1 METHOD TO ACCELERATE BIODEGRADATION OF ALIPHATIC-AROMATIC CO-POLYESTERS BY ENZYMATIC TREATMENT E.I. DU PONT DE NEMOURS AND COMPANY (US) 2005-12-15 WO disclosed
US-20050261465-A1 Method to accelerate biodegradation of aliphatic-aromatic co-polyesters by enzymatic treatment E.I. DU PONT DE NEMOURS AND COMPANY 2005-11-24 US disclosed
US-4403049-A POLYMERIZING A SPINNING OIL OF EPOXY COMPOUND, AN ETHYLENE UREA UNITIKA LIMITED (JP) 1983-09-06 US disclosed