Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | TLR2 | O60603 | 1/20 | 0.48 |
| ▸ | NSD2 | O96028 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MPI | P34949 | 1/20 | 0.48 |
| ▸ | GRK6 | P43250 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.48 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25062393 | 0.90 | HDAC4 (0.54) | HDAC4HDAC6L3MBTL1NPC1RAB9A | |
| SCHEMBL21940624 | 0.86 | HDAC4 (0.54) | HDAC4HDAC6L3MBTL1NPC1RAB9A | |
| SCHEMBL449698 | 0.85 | HDAC4 (0.73) | HDAC4HDAC6L3MBTL1NPC1RAB9A | |
| SCHEMBL8631493 | 0.84 | HDAC4 (0.59) | HDAC4HDAC6L3MBTL1NPC1RAB9A | |
| SCHEMBL1827714 | 0.83 | HDAC4 (0.51) | HDAC4HDAC6L3MBTL1NPC1RAB9A | |
| SCHEMBL20029969 | 0.83 | L3MBTL1 (0.41) | HDAC4HDAC6L3MBTL1NPC1RAB9A | |
| SCHEMBL13079492 | 0.83 | HDAC4 (0.54) | HDAC4HDAC6L3MBTL1NPC1RAB9A | |
| SCHEMBL29617026 | 0.81 | HDAC4 (0.64) | HDAC4HDAC6L3MBTL1NPC1RAB9A | |
| SCHEMBL28668738 | 0.81 | HDAC4 (0.59) | HDAC4HDAC6L3MBTL1NPC1RAB9A | |
| SCHEMBL28656003 | 0.81 | HDAC4 (0.59) | HDAC4HDAC6L3MBTL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200131144-A1 | AMINE OR (THIO)AMIDE CONTAINING LXR MODULATORS | PHENEX-FXR GMBH (DE) | 2020-04-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200131144-A1 | AMINE OR (THIO)AMIDE CONTAINING LXR MODULATORS | NR1H2, NR1H3, NR1H4 | HDAC4 798/4885HDAC6 1286/4885L3MBTL1 2981/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.