SCHEMBL449698

SCHEMBL449698

CCOC(=O)c1ccc(C(=O)OCC)o1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 1/20 0.73
HDAC6 Q9UBN7 1/20 0.73
ALDH1A1 P00352 7/20 0.55
MAPT P10636 3/20 0.55
L3MBTL1 Q9Y468 2/20 0.55
KDM4E B2RXH2 2/20 0.55
TLR2 O60603 1/20 0.55
NSD2 O96028 1/20 0.55
POLB P06746 1/20 0.55
PKM P14618 1/20 0.55
MPI P34949 1/20 0.55
GRK6 P43250 1/20 0.55
RECQL P46063 1/20 0.55
TLR1 Q15399 1/20 0.55
TLR6 Q9Y2C9 1/20 0.55
TSHR P16473 3/20 0.54
LMNA P02545 3/20 0.53
NPC1 O15118 1/20 0.53
RAB9A P51151 1/20 0.53
GAA P10253 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28427399 0.92 HDAC4 (0.65) HDAC4HDAC6ALDH1A1MAPTL3MBTL1
SCHEMBL14052281 0.92 HDAC4 (0.70) HDAC4HDAC6ALDH1A1MAPTL3MBTL1
SCHEMBL1828976 0.92 HDAC4 (0.65) HDAC4HDAC6ALDH1A1MAPTL3MBTL1
SCHEMBL29617026 0.91 HDAC4 (0.64) HDAC4HDAC6ALDH1A1MAPTL3MBTL1
SCHEMBL3066300 0.90 HDAC4 (0.63) HDAC4HDAC6ALDH1A1MAPTL3MBTL1
SCHEMBL28655961 0.90 HDAC4 (0.63) HDAC4HDAC6ALDH1A1MAPTL3MBTL1
SCHEMBL3824966 0.90 HDAC4 (0.63) HDAC4HDAC6ALDH1A1MAPTL3MBTL1
SCHEMBL669793 0.90 HDAC4 (0.62) HDAC4HDAC6ALDH1A1MAPTL3MBTL1
SCHEMBL26303144 0.89 HDAC4 (0.61) HDAC4HDAC6ALDH1A1MAPTL3MBTL1
SCHEMBL2632284 0.88 HDAC4 (0.60) HDAC4HDAC6ALDH1A1MAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 209 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4700064-A1 AMORPHOUS COPOLYAMIDES OBTAINED FROM 2,5-FURANDICARBOXYLIC ACID ARKEMA FRANCE (FR) 2026-02-25 EP claimed
EP-4692163-A1 POLYESTER ELASTOMER CONTAINING FURAN RING, AND PREPARATION METHOD THEREFOR AND USE THEREOF China Petroleum & Chemical Corporation (CN) 2026-02-11 EP claimed
EP-4582466-A1 PROCESS FOR THE MANUFACTURE OF SEMI-AROMATIC POLYAMIDES ARKEMA FRANCE (FR) 2025-07-09 EP claimed
WO-2024207746-A1 POLYESTER ELASTOMER CONTAINING FURAN RING, AND PREPARATION METHOD THEREFOR AND USE THEREOF 中国石油化工股份有限公司 2024-10-10 WO claimed
CN-117964884-A Polyester elastomer based on ethylene engineering byproducts, preparation method and application 宁波职业技术学院 2024-05-03 CN claimed
CN-115286598-B Synthesis method of 2, 5-furandicarboxylic acid diester compound 中国石油化工股份有限公司 2024-04-26 CN claimed
CN-117164849-A Preparation method of furyl flexible polyamide 中科国生(杭州)科技有限公司 2023-12-05 CN claimed
CN-116715834-A High-strength high-toughness 2, 5-furandicarboxylic acid copolyester and preparation method thereof 重庆文理学院 2023-09-08 CN claimed
CN-115304754-B 2, 5-furandicarboxylic acid based copolyester material and preparation method thereof 中国科学院大连化学物理研究所 2023-08-08 CN claimed
CN-116284705-A Furanedicarboxylic acid ester bio-based crosslinkable elastomer and preparation method thereof 湖北大学 2023-06-23 CN claimed
WO-2016202858-A1 PROCESSES FOR THE FORMATION OF FURANDICARBOXYLIC ACID (FDCA) VIA A MULTISTEP BIOCATALYTIC OXIDATION REACTION OF 5-HYDROXYMETHYLFURFURAL (HMF) BIOME BIOPLASTICS LIMITED (GB) 2016-12-22 WO claimed
US-9133153-B2 Method for manufacturing compounds including nitrile functions RHODIA OPERATIONS (FR) 2015-09-15 US claimed
US-20140343304-A1 METHOD FOR MANUFACTURING COMPOUNDS INCLUDING NITRILE FUNCTIONS RHODIA OPERATIONS (FR) 2014-11-20 US claimed
EP-2776536-A1 A METHOD FOR PRODUCING BIOBASED CHEMICALS FROM PLANT BIOMASS Vertichem Corporation (CA) 2014-09-17 EP claimed
WO-2013089928-A1 A METHOD FOR PRODUCING BIOBASED CHEMICALS FROM PLANT BIOMASS Vertichem Corporation (CA) 2013-06-20 WO claimed
US-20130115661-A1 METHOD FOR PRODUCING BIOBASED CHEMICALS FROM CULTIVATED PLANT BIOMASS THESIS CHEMISTRY, LLC (US) 2013-05-09 US claimed
US-20130115653-A1 METHOD FOR PRODUCING BIOBASED CHEMICALS FROM WOODY BIOMASS THESIS CHEMISTRY, LLC (US) 2013-05-09 US claimed
US-20130116424-A1 METHOD FOR PRODUCING BIOBASED CHEMICALS FROM PLANT BIOMASS THESIS CHEMISTRY, LLC (US) 2013-05-09 US claimed
US-20130115654-A1 METHOD FOR PRODUCING BIOBASED CHEMICALS FROM AGRICULTURAL BIOMASS THESIS CHEMISTRY, LLC (US) 2013-05-09 US claimed
US-20090018264-A1 RESIN COMPOSITION CANON KABUSHIKI KAISHA (JP) 2009-01-15 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140343304-A1 METHOD FOR MANUFACTURING COMPOUNDS INCLUDING NITRILE FUNCTIONS NOS1, NOS2, NOS3 HDAC4 3834/4885HDAC6 3472/4885ALDH1A1 182/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.