Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 4/20 | 0.46 |
| ▸ | CTSB | P07858 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.45 |
| ▸ | CTSS | P25774 | 2/20 | 0.43 |
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
| ▸ | CDK2 | P24941 | 4/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 3/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21939547 | 0.74 | ADORA3 (0.54) | ADORA3ADORA2AADORA1 | |
| SCHEMBL16774261 | 0.73 | ADORA3 (0.83) | ADORA3ADORA2AADORA1 | |
| SCHEMBL20122208 | 0.73 | ADORA3 (0.83) | ADORA3ADORA2AADORA1 | |
| SCHEMBL20122112 | 0.72 | ADORA3 (0.56) | ADORA3ADORA2AADORA1 | |
| SCHEMBL24615116 | 0.72 | ADORA3 (0.59) | ADORA3ADORA2A | |
| SCHEMBL24615197 | 0.71 | ADORA3 (0.49) | ADORA3 | |
| SCHEMBL22359741 | 0.71 | ADORA3 (0.56) | ADORA3ADORA2AADORA1 | |
| SCHEMBL18352572 | 0.71 | ADORA3 (0.71) | ADORA3ADORA2AADORA1 | |
| SCHEMBL20122119 | 0.70 | ADORA3 (0.61) | ADORA3ADORA2AADORA1 | |
| SCHEMBL21939409 | 0.69 | SLC6A2 (0.58) | ADORA3ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020061211-A1 | USE OF HIGHLY-SELECTIVE ADENOSINE 3A RECEPTOR SUBTYPE AGONISTS | SAINT LOUIS UNIVERSITY (US) | 2020-03-26 | — | — | WO | disclosed |