Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 18/20 | 0.75 |
| ▸ | ADORA1 | P30542 | 10/20 | 0.75 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.65 |
| ▸ | HTR2B | P41595 | 1/20 | 0.65 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.59 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19807422 | 0.93 | ADORA3 (0.75) | ADORA3ADORA1ADORA2AHTR2BTMIGD3 | |
| SCHEMBL19503865 | 0.88 | ADORA3 (0.76) | ADORA3ADORA1ADORA2AHTR2BABCG2 | |
| SCHEMBL16774394 | 0.86 | ADORA3 (1.00) | ADORA3ADORA1ADORA2AHTR2BTMIGD3 | |
| SCHEMBL19464994 | 0.86 | ADORA3 (1.00) | ADORA3ADORA1ADORA2AHTR2BTMIGD3 | |
| SCHEMBL22933145 | 0.86 | ADORA3 (1.00) | ADORA3ADORA1ADORA2AHTR2BTMIGD3 | |
| SCHEMBL20122154 | 0.86 | ADORA3 (1.00) | ADORA3ADORA1ADORA2AHTR2BTMIGD3 | |
| SCHEMBL19464997 | 0.86 | ADORA3 (1.00) | ADORA3ADORA1ADORA2AHTR2BTMIGD3 | |
| SCHEMBL21779297 | 0.85 | ADORA3 (0.80) | ADORA3ADORA1ADORA2AABCG2KCNH2 | |
| SCHEMBL20122056 | 0.85 | ADORA3 (0.80) | ADORA3ADORA1ADORA2AABCG2KCNH2 | |
| SCHEMBL21779333 | 0.85 | ADORA3 (0.80) | ADORA3ADORA1ADORA2AABCG2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020061211-A1 | USE OF HIGHLY-SELECTIVE ADENOSINE 3A RECEPTOR SUBTYPE AGONISTS | SAINT LOUIS UNIVERSITY (US) | 2020-03-26 | — | — | WO | disclosed |