Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 18/20 | 0.76 |
| ▸ | ADORA1 | P30542 | 13/20 | 0.76 |
| ▸ | ADORA2A | P29274 | 13/20 | 0.76 |
| ▸ | PPARG | P37231 | 3/20 | 0.65 |
| ▸ | PPARD | Q03181 | 3/20 | 0.65 |
| ▸ | HTR2B | P41595 | 2/20 | 0.64 |
| ▸ | HTR2C | P28335 | 1/20 | 0.64 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19807422 | 0.92 | ADORA3 (0.75) | ADORA3ADORA1ADORA2AHTR2BHTR2C | |
| SCHEMBL21940221 | 0.88 | ADORA3 (0.75) | ADORA3ADORA1ADORA2AHTR2BABCG2 | |
| SCHEMBL19503866 | 0.88 | ADORA3 (0.75) | ADORA3ADORA1ADORA2APPARDHTR2B | |
| SCHEMBL19807555 | 0.86 | ADORA3 (1.00) | ADORA3ADORA1ADORA2AHTR2BADORA2B | |
| SCHEMBL13388266 | 0.86 | ADORA3 (1.00) | ADORA3ADORA1ADORA2AHTR2BADORA2B | |
| SCHEMBL12264931 | 0.86 | ADORA3 (1.00) | ADORA3ADORA1ADORA2AHTR2BADORA2B | |
| SCHEMBL29775232 | 0.86 | ADORA3 (1.00) | ADORA3ADORA1ADORA2AHTR2BADORA2B | |
| SCHEMBL29524240 | 0.86 | ADORA3 (1.00) | ADORA3ADORA1ADORA2AHTR2BADORA2B | |
| SCHEMBL19465000 | 0.86 | ADORA3 (1.00) | ADORA3ADORA1ADORA2AHTR2BADORA2B | |
| SCHEMBL29316525 | 0.86 | ADORA3 (0.71) | ADORA3ADORA1ADORA2APPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3445368-B1 | COMPOUNDS AND METHODS FOR TREATING NEUROLOGICAL AND CARDIOVASCULAR CONDITIONS | ASTROCYTE PHARMACEUTICALS INC (US) | 2024-07-17 | — | — | EP | disclosed |
| WO-2019157317-A1 | COMPOUNDS AND METHODS FOR TREATING ADDICTION AND RELATED DISORDERS | ASTROCYTE PHARMACEUTICALS, INC. (US) | 2019-08-15 | — | — | WO | disclosed |
| WO-2017185061-A1 | COMPOUNDS AND METHODS FOR TREATING NEUROLOGICAL AND CARDIOVASCULAR CONDITIONS | ASTROCYTE PHARMACEUTICALS, INC. (US) | 2017-10-26 | — | — | WO | disclosed |