Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.47 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 3/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15899233 | 0.83 | ALDH1A1 (0.40) | TSHRALDH1A1THRBFAAHCNR1 | |
| SCHEMBL296975 | 0.82 | TSHR (0.48) | TSHRLMNACHRM2CHRM4CHRM1 | |
| SCHEMBL15899236 | 0.82 | ALDH1A1 (0.39) | TSHRALDH1A1THRBFAAHGABRP | |
| SCHEMBL11520287 | 0.80 | ALDH1A1 (0.42) | TSHRALDH1A1THRBFAAHHSD17B10 | |
| SCHEMBL16244181 | 0.79 | TSHR (0.50) | TSHRLMNACHRM2CHRM4CHRM5 | |
| SCHEMBL28762370 | 0.79 | TSHR (0.50) | TSHRLMNACHRM2CHRM4CHRM5 | |
| SCHEMBL514364 | 0.79 | — | — | |
| SCHEMBL11520292 | 0.76 | ALDH1A1 (0.38) | TSHRALDH1A1THRB | |
| SCHEMBL28945815 | 0.75 | LMNA (0.50) | TSHRLMNACHRM2CHRM4CHRM5 | |
| SCHEMBL223940 | 0.75 | LMNA (0.50) | TSHRLMNACHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3063148-B1 | AZABENZIMIDAZOLE DERIVATIVES | BOEHRINGER INGELHEIM INT (DE) | 2020-04-29 | — | — | EP | disclosed |