Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21940603 | 0.81 | KDM1A (0.43) | KDM1ATSHRALOX15ATMGPR119 | |
| SCHEMBL21940363 | 0.81 | KDM1A (0.43) | KDM1ATSHRALOX15ATMGPR119 | |
| SCHEMBL14272806 | 0.78 | KDM1A (0.49) | KDM1ATSHRALOX15ATMGPR119 | |
| SCHEMBL6397393 | 0.78 | KDM1A (0.49) | KDM1ATSHRALOX15ATMGPR119 | |
| SCHEMBL6393580 | 0.78 | KDM1A (0.49) | KDM1ATSHRALOX15ATMGPR119 | |
| SCHEMBL14272818 | 0.78 | KDM1A (0.49) | KDM1ATSHRALOX15ATMGPR119 | |
| SCHEMBL21940373 | 0.76 | TSHR (0.39) | TSHRALOX15ATMGPR119STS | |
| SCHEMBL14272805 | 0.76 | TSHR (0.46) | KDM1ATSHRALOX15ATMGPR119 | |
| SCHEMBL31645476 | 0.76 | KDM1A (0.45) | KDM1ATSHRALOX15ATMGPR119 | |
| SCHEMBL14272804 | 0.75 | KDM1A (0.46) | KDM1ATSHRALOX15ATMGPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3867238-B1 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS | ARRAY BIOPHARMA INC (US) | 2023-06-07 | — | — | EP | disclosed |
| WO-2020081848-A1 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2020-04-23 | — | — | WO | disclosed |