Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 6/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | STS | P08842 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29506188 | 0.83 | TSHR (0.38) | TSHRALOX15NAMPTGPR119ATM | |
| SCHEMBL29832328 | 0.83 | TSHR (0.38) | TSHRALOX15NAMPTGPR119ATM | |
| SCHEMBL21940374 | 0.83 | TSHR (0.38) | TSHRALOX15NAMPTGPR119ATM | |
| SCHEMBL29506184 | 0.83 | TSHR (0.38) | TSHRALOX15NAMPTGPR119ATM | |
| SCHEMBL21941112 | 0.83 | TSHR (0.38) | TSHRALOX15NAMPTGPR119ATM | |
| SCHEMBL21940622 | 0.78 | STS (0.40) | NAMPTSTS | |
| SCHEMBL23024159 | 0.77 | ROCK2 (0.42) | TSHRALOX15NAMPTGPR119ATM | |
| SCHEMBL21940602 | 0.76 | KDM1A (0.45) | TSHRALOX15GPR119ATMSTS | |
| SCHEMBL23024480 | 0.74 | GPR119 (0.41) | TSHRALOX15NAMPTGPR119ATM | |
| SCHEMBL30999897 | 0.74 | GPR119 (0.41) | TSHRALOX15NAMPTGPR119ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3867238-B1 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS | ARRAY BIOPHARMA INC (US) | 2023-06-07 | — | — | EP | disclosed |
| WO-2020081848-A1 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS | ARRAY BIOPHARMA INC. (US) | 2020-04-23 | — | — | WO | disclosed |