Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL612971 | 1.00 | OPRM1 (0.37) | OPRM1OPRD1OPRK1 | |
| SCHEMBL3191321 | 0.99 | OPRM1 (0.39) | OPRM1OPRD1OPRK1 | |
| SCHEMBL611541 | 0.99 | OPRM1 (0.39) | OPRM1OPRD1OPRK1 | |
| SCHEMBL10287095 | 0.99 | OPRM1 (0.39) | OPRM1OPRD1OPRK1 | |
| SCHEMBL612983 | 0.99 | OPRM1 (0.39) | OPRM1OPRD1OPRK1 | |
| SCHEMBL15463121 | 0.90 | NMT2 (0.42) | — | |
| SCHEMBL16031728 | 0.88 | PDE4A (0.35) | — | |
| SCHEMBL13559385 | 0.87 | MEN1 (0.43) | — | |
| SCHEMBL10235806 | 0.86 | BCHE (0.39) | OPRM1OPRD1OPRK1 | |
| SCHEMBL10235827 | 0.85 | BCHE (0.40) | OPRM1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2844636-B1 | METHODS FOR THE TREATMENT OF PROLIFERATIVE DIABETIC RETINOPATHY | ACUCELA INC (US) | 2020-04-22 | — | — | EP | disclosed |