SCHEMBL21942448

SCHEMBL21942448

C[C@@H]1CC12CCN(C=O)CC2

nearest known ligand 0.46

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ NAMPT P43490 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18357662 0.70 NAMPT (0.42) NAMPT
SCHEMBL19122426 0.70 NAMPT (0.42) NAMPT
SCHEMBL14409817 0.70 HSD17B10 (0.30) —
SCHEMBL16984331 0.70 NAMPT (0.42) NAMPT
SCHEMBL23139132 0.70 ALPL (0.31) —
SCHEMBL24880872 0.69 NAMPT (0.41) NAMPT
SCHEMBL4574110 0.68 — —
SCHEMBL16974723 0.67 HSD17B10 (0.31) —
SCHEMBL12068440 0.67 HSD17B10 (0.32) —
SCHEMBL14417818 0.67 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3636637-A1 INHIBITING FATTY ACID SYNTHASE (FASN) Forma Therapeutics, Inc. (US) 2020-04-15 — — EP disclosed
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