Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | SCN1A | P35498 | 1/20 | 0.32 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.32 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19122426 | 1.00 | NAMPT (0.42) | NAMPTSCN1ASCN2ASCN3A | |
| SCHEMBL18357662 | 1.00 | NAMPT (0.42) | NAMPTSCN1ASCN2ASCN3A | |
| SCHEMBL16984329 | 0.91 | NAMPT (0.38) | NAMPT | |
| SCHEMBL26463221 | 0.84 | — | — | |
| SCHEMBL16330613 | 0.84 | — | — | |
| SCHEMBL14431977 | 0.84 | — | — | |
| SCHEMBL19122812 | 0.79 | NAMPT (0.32) | NAMPT | |
| SCHEMBL25820270 | 0.79 | OPRM1 (0.38) | NAMPT | |
| SCHEMBL16659569 | 0.79 | NAMPT (0.32) | NAMPT | |
| SCHEMBL27267506 | 0.79 | ALDH1A1 (0.32) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203057-A1 | FIVE-MEMBERED HETEROAROMATIC IMIDAZOLE COMPOUND AND USE THEREOF | HANGZHOU SCIWIND BIOSCIENCES CO., LTD (CN) | 2023-06-29 | — | — | US | disclosed |
| US-20230203057-A1 | FIVE-MEMBERED HETEROAROMATIC IMIDAZOLE COMPOUND AND USE THEREOF | HANGZHOU SCIWIND BIOSCIENCES CO., LTD (CN) | 2023-06-29 | — | — | US | disclosed |
| US-11542272-B2 | Five-membered heteroaryl-fused imidazole compound and application thereof | HANGZHOU SCIWIND BIOSCIENCES CO., LTD (CN) | 2023-01-03 | — | — | US | disclosed |
| US-20220135588-A1 | Five-Membered Heteroaryl-Fused Imidazole Compound And Application Thereof | HANGZHOU SCIWIND BIOSCIENCES CO., LTD (CN) | 2022-05-05 | — | — | US | disclosed |
| US-20170196862-A2 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2017-07-13 | — | — | US | disclosed |
| WO-2017001660-A1 | ANTIBACTERIAL COMPOUNDS | JANSSEN SCIENCES IRELAND UC (IE) | 2017-01-05 | — | — | WO | disclosed |
| US-20150216168-A1 | USE OF SUBSTITUTED 2-AMIDOBENZIMIDAZOLES, 2-AMIDOBENZOXAZOLES AND 2-AMIDOBENZOTHIAZOLES OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS | BAYER CROPSCIENCE AG (DE) | 2015-08-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220135588-A1 | Five-Membered Heteroaryl-Fused Imidazole Compound And Application Thereof | GLP1R, GIPR, GPR119 | NAMPT 3423/4885SCN1A 2406/4885SCN2A 2076/4885 |
| US-20230203057-A1 | FIVE-MEMBERED HETEROAROMATIC IMIDAZOLE COMPOUND AND USE THEREOF | GLP1R, GIPR, GPR119 | NAMPT 3102/4885SCN1A 2572/4885SCN2A 2368/4885 |
| US-11542272-B2 | Five-membered heteroaryl-fused imidazole compound and application thereof | GLP1R, GIPR, GPR119 | NAMPT 3423/4885SCN1A 2406/4885SCN2A 2076/4885 |
| US-20150216168-A1 | USE OF SUBSTITUTED 2-AMIDOBENZIMIDAZOLES, 2-AMIDOBENZOXAZOLES AND 2-AMIDOBENZOTHIAZOLES OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS | ABAT, AAK1, AGXT | NAMPT 2174/4885SCN1A 3312/4885SCN2A 1763/4885 |
| US-20170196862-A2 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | CFTR, SCNN1B, SLC26A4 | NAMPT 2312/4885SCN1A 85/4885SCN2A 143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.