Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.84 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.84 |
| ▸ | RORC | P51449 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.46 |
| ▸ | PPARA | Q07869 | 4/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.43 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2194005 | 0.91 | SETD7 (1.00) | SETD7EHMT2RORCNR1H4PPARA | |
| SCHEMBL29365843 | 0.91 | SETD7 (1.00) | SETD7EHMT2RORCNR1H4PPARA | |
| SCHEMBL2196761 | 0.90 | SETD7 (0.81) | SETD7EHMT2RORCPPARAHIF1A | |
| SCHEMBL2191400 | 0.89 | SETD7 (0.67) | SETD7EHMT2F2F10PRSS1 | |
| SCHEMBL2192864 | 0.81 | SETD7 (0.68) | SETD7EHMT2RORCHIF1AF2 | |
| SCHEMBL12492311 | 0.80 | SETD7 (0.66) | SETD7EHMT2RORCPPARAHIF1A | |
| SCHEMBL12492228 | 0.79 | SETD7 (0.65) | SETD7EHMT2RORCHIF1AF2 | |
| SCHEMBL12491602 | 0.78 | SETD7 (0.63) | SETD7EHMT2RORCPPARAHIF1A | |
| SCHEMBL12489925 | 0.77 | SETD7 (0.75) | SETD7EHMT2RORCNR1H4PPARA | |
| SCHEMBL2192171 | 0.77 | SETD7 (0.60) | SETD7EHMT2RORCNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011082098-A1 | LYSINE AND ARGININE METHYLTRANSFERASE INHIBITORS FOR TREATING CANCER | THE ROCKEFELLER UNIVERSITY (US) | 2011-07-07 | — | — | WO | disclosed |