Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.60 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | PPM1D | O15297 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2192864 | 0.85 | SETD7 (0.68) | SETD7EHMT2HDAC8HDAC6RORC | |
| SCHEMBL2196761 | 0.84 | SETD7 (0.81) | SETD7EHMT2HDAC8HDAC6RORC | |
| SCHEMBL2191641 | 0.83 | SETD7 (0.58) | SETD7EHMT2RORCDHODHMEN1 | |
| SCHEMBL2192976 | 0.81 | SETD7 (0.55) | SETD7EHMT2RORCDHODHALDH1A1 | |
| SCHEMBL2194283 | 0.77 | SETD7 (0.84) | SETD7EHMT2RORCMEN1NPC1 | |
| SCHEMBL2193598 | 0.76 | SETD7 (0.61) | SETD7EHMT2RORCALDH1A1MAPT | |
| SCHEMBL2192071 | 0.76 | SETD7 (0.56) | SETD7EHMT2RORCMEN1NPC1 | |
| SCHEMBL2196465 | 0.76 | SETD7 (0.51) | SETD7EHMT2RORCDHODH | |
| SCHEMBL2194005 | 0.75 | SETD7 (1.00) | SETD7EHMT2RORCNPC1RAB9A | |
| SCHEMBL29365843 | 0.75 | SETD7 (1.00) | SETD7EHMT2RORCNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011082098-A1 | LYSINE AND ARGININE METHYLTRANSFERASE INHIBITORS FOR TREATING CANCER | THE ROCKEFELLER UNIVERSITY (US) | 2011-07-07 | — | — | WO | disclosed |