Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.68 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.68 |
| ▸ | RORC | P51449 | 2/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 2/20 | 0.45 |
| ▸ | F10 | P00742 | 2/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.45 |
| ▸ | CPT2 | P23786 | 1/20 | 0.43 |
| ▸ | CPT1A | P50416 | 1/20 | 0.43 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2196761 | 0.91 | SETD7 (0.81) | SETD7EHMT2RORCHIF1AF2 | |
| SCHEMBL2193598 | 0.86 | SETD7 (0.61) | SETD7EHMT2RORCF2F10 | |
| SCHEMBL2192171 | 0.85 | SETD7 (0.60) | SETD7EHMT2RORCFFAR1FFAR4 | |
| SCHEMBL2191641 | 0.83 | SETD7 (0.58) | SETD7EHMT2RORCPPARGPOLB | |
| SCHEMBL2194005 | 0.81 | SETD7 (1.00) | SETD7EHMT2RORCHIF1AF2 | |
| SCHEMBL2194283 | 0.81 | SETD7 (0.84) | SETD7EHMT2RORCHIF1AF2 | |
| SCHEMBL29365843 | 0.81 | SETD7 (1.00) | SETD7EHMT2RORCHIF1AF2 | |
| SCHEMBL2192976 | 0.81 | SETD7 (0.55) | SETD7EHMT2RORCPPARGPOLB | |
| SCHEMBL2196465 | 0.79 | SETD7 (0.51) | SETD7EHMT2RORC | |
| SCHEMBL2192071 | 0.78 | SETD7 (0.56) | SETD7EHMT2RORCPOLBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011082098-A1 | LYSINE AND ARGININE METHYLTRANSFERASE INHIBITORS FOR TREATING CANCER | THE ROCKEFELLER UNIVERSITY (US) | 2011-07-07 | — | — | WO | disclosed |