Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | TACR3 | P29371 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30579512 | 0.75 | TACR3 (0.38) | KMT2AMEN1GAACYP2C9CYP2C19 | |
| SCHEMBL1642227 | 0.74 | ALDH1A1 (0.39) | ALDH1A1TMEM97SIGMAR1KMT2AMEN1 | |
| SCHEMBL9554965 | 0.70 | TMEM97 (0.41) | ALDH1A1TMEM97SIGMAR1 | |
| SCHEMBL5888790 | 0.68 | GAA (0.39) | KMT2AMEN1GAACYP2C9CYP2C19 | |
| SCHEMBL1189580 | 0.67 | LMNA (0.41) | ALDH1A1TMEM97SIGMAR1KMT2AMEN1 | |
| SCHEMBL1189315 | 0.67 | LMNA (0.41) | ALDH1A1TMEM97SIGMAR1KMT2AMEN1 | |
| SCHEMBL1190461 | 0.67 | LMNA (0.41) | ALDH1A1TMEM97SIGMAR1KMT2AMEN1 | |
| SCHEMBL1190560 | 0.67 | LMNA (0.41) | ALDH1A1TMEM97SIGMAR1KMT2AMEN1 | |
| SCHEMBL5927756 | 0.65 | GAA (0.39) | ALDH1A1TMEM97SIGMAR1GAACYP2C9 | |
| SCHEMBL5927757 | 0.65 | GAA (0.39) | ALDH1A1TMEM97SIGMAR1GAACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7977336-B2 | Aminopyrimidine derivatives as PLK1 inhibitors | BANYU PHARMACEUTICAL CO. LTD (JP) | 2011-07-12 | — | — | US | disclosed |