Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.59 |
| ▸ | FAAH | O00519 | 2/20 | 0.57 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12509148 | 0.93 | FAAH (0.62) | FAAHNR4A2NPC1 | |
| SCHEMBL2195419 | 0.92 | FAAH (0.56) | PPARAFAAH | |
| SCHEMBL2195988 | 0.92 | NR1H4 (0.61) | FAAHNR1H4NPC1 | |
| SCHEMBL2194608 | 0.90 | FAAH (0.60) | FAAHNPC1 | |
| SCHEMBL2193693 | 0.90 | FAAH (0.58) | PPARAFAAHNR4A2 | |
| SCHEMBL2196227 | 0.89 | MAPT (0.54) | PPARAFAAHEPHX2NPC1 | |
| SCHEMBL12509344 | 0.88 | FAAH (0.58) | FAAHEPHX2NPC1 | |
| SCHEMBL12509226 | 0.88 | FAAH (0.58) | FAAHNPC1 | |
| SCHEMBL12509231 | 0.88 | FAAH (0.57) | FAAHNPC1 | |
| SCHEMBL12509042 | 0.87 | FAAH (0.53) | PPARAFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110172230-A1 | UREA COMPOUND OR SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2011-07-14 | — | — | US | disclosed |
| US-20110172230-A1 | UREA COMPOUND OR SALT THEREOF | ASTELLAS PHARMA INC. (JP) | 2011-07-14 | — | — | US | disclosed |
| EP-2065369-A1 | UREA COMPOUND OR SALT THEREOF | Astellas Pharma Inc. (JP) | 2009-06-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110172230-A1 | UREA COMPOUND OR SALT THEREOF | FAAH, FAAH2, UTS2R | PPARA 614/4885FAAH 1/4885NR4A2 3133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.