SCHEMBL21944404

SCHEMBL21944404

CC(C)(C)c1cc(-c2cc(-c3ccc4c(c3)c3ccccc3n4-c3ccc4ccccc4c3)c(-c3cc(C(C)(C)C)cc(C(C)(C)C)c3)cc2-c2ccc3c(c2)c2ccccc2n3-c2ccc3ccccc3c2)cc(C(C)(C)C)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TUBB4A P04350 1/20 0.34
TUBB P07437 1/20 0.34
TUBA3C P0DPH7 1/20 0.34
TUBA1B P68363 1/20 0.34
TUBA4A P68366 1/20 0.34
TUBB4B P68371 1/20 0.34
TUBB3 Q13509 1/20 0.34
TUBB2A Q13885 1/20 0.34
TUBB8 Q3ZCM7 1/20 0.34
TUBA3E Q6PEY2 1/20 0.34
TUBA1A Q71U36 1/20 0.34
TUBA1C Q9BQE3 1/20 0.34
TUBB6 Q9BUF5 1/20 0.34
TUBB2B Q9BVA1 1/20 0.34
TUBB1 Q9H4B7 1/20 0.34
MAPK10 P53779 2/20 0.33
MAPK9 P45984 1/20 0.33
KDM4E B2RXH2 1/20 0.33
ATM Q13315 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21943977 0.88 KDM4E (0.40) KDM4EATML3MBTL1PPARGALDH1A1
SCHEMBL20825697 0.88 KDM4E (0.37) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL21944028 0.86 KDM4E (0.42) KDM4EATML3MBTL1PPARGALDH1A1
SCHEMBL21943975 0.86 KDM4E (0.49) KDM4EATML3MBTL1PPARGHPGD
SCHEMBL25443956 0.84 PPARG (0.38) KDM4EATML3MBTL1PPARGALDH1A1
SCHEMBL21943976 0.83 PPARG (0.37) KDM4EATML3MBTL1PPARGALDH1A1
SCHEMBL21944393 0.83 L3MBTL1 (0.40) KDM4EATML3MBTL1PPARGALDH1A1
SCHEMBL21944395 0.83 L3MBTL1 (0.40) KDM4EATML3MBTL1PPARGALDH1A1
SCHEMBL18717920 0.82 KDM4E (0.41) TUBB4ATUBBTUBA3CTUBA1BTUBA4A
SCHEMBL19735303 0.82 KDM4E (0.41) MAPK10MAPK9KDM4EATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230145492-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, IMAGE PICKUP ELEMENT, AND IMAGE PICKUP APPARATUS CANON KK (JP) 2023-05-11 US disclosed
US-20230145492-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, IMAGE PICKUP ELEMENT, AND IMAGE PICKUP APPARATUS CANON KK (JP) 2023-05-11 US disclosed
US-20200119281-A1 ORGANIC PHOTOELECTRIC CONVERSION ELEMENT, IMAGE PICKUP ELEMENT, AND IMAGE PICKUP APPARATUS CANON KABUSHIKI KAISHA (JP) 2020-04-16 US disclosed