SCHEMBL20825697

SCHEMBL20825697

CC(C)(C)c1cc(-c2ccc3c(c2)c2ccccc2n3-c2ccc3cc(-c4ccc5cc(-n6c7ccccc7c7cc(-c8cc(C(C)(C)C)cc(C(C)(C)C)c8)ccc76)ccc5c4)ccc3c2)cc(C(C)(C)C)c1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
ATM Q13315 1/20 0.37
PPARG P37231 4/20 0.35
PTGES O14684 1/20 0.35
RXRB P28702 3/20 0.34
RXRA P19793 2/20 0.34
TUBB4A P04350 1/20 0.34
TUBB P07437 1/20 0.34
TUBA3C P0DPH7 1/20 0.34
TUBA1B P68363 1/20 0.34
TUBA4A P68366 1/20 0.34
TUBB4B P68371 1/20 0.34
TUBB3 Q13509 1/20 0.34
TUBB2A Q13885 1/20 0.34
TUBB8 Q3ZCM7 1/20 0.34
TUBA3E Q6PEY2 1/20 0.34
TUBA1A Q71U36 1/20 0.34
TUBA1C Q9BQE3 1/20 0.34
TUBB6 Q9BUF5 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21944404 0.88 TUBB4A (0.34) KDM4EL3MBTL1ATMPPARGTUBB4A
SCHEMBL9890899 0.84 PPARG (0.39) KDM4EL3MBTL1ATMPPARGPTGES
SCHEMBL10130216 0.83 ESR1 (0.43) KDM4EL3MBTL1ATMTUBB4ATUBB
SCHEMBL31450454 0.83 ESR1 (0.43) KDM4EL3MBTL1ATMTUBB4ATUBB
SCHEMBL29517009 0.83 ESR1 (0.43) KDM4EL3MBTL1ATMTUBB4ATUBB
SCHEMBL11981041 0.83 KDM4E (0.46) KDM4EL3MBTL1ATMTUBB4ATUBB
SCHEMBL15480403 0.83 KDM4E (0.46) KDM4EL3MBTL1ATMTUBB4ATUBB
SCHEMBL30475208 0.83 KDM4E (0.46) KDM4EL3MBTL1ATMTUBB4ATUBB
SCHEMBL25777639 0.83 KDM4E (0.41) KDM4EL3MBTL1ATMPPARGPTGES
SCHEMBL24601329 0.83 KDM4E (0.33) KDM4EL3MBTL1ATMPPARGRXRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11793074-B2 Organic compound and photoelectric conversion element CANON KABUSHIKI KAISHA (JP) 2023-10-17 US disclosed
US-11793074-B2 Organic compound and photoelectric conversion element CANON KABUSHIKI KAISHA (JP) 2023-10-17 US disclosed
US-20210057653-A1 ORGANIC COMPOUND AND PHOTOELECTRIC CONVERSION ELEMENT CANON KK (JP) 2021-02-25 US disclosed
US-10868260-B2 Organic compound and photoelectric conversion element CANON KABUSHIKI KAISHA (JP) 2020-12-15 US disclosed
US-20190088885-A1 ORGANIC COMPOUND AND PHOTOELECTRIC CONVERSION ELEMENT CANON KABUSHIKI KAISHA (JP) 2019-03-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11793074-B2 Organic compound and photoelectric conversion element CRY1, CYP1A1, CCNE2 KDM4E 1730/4885L3MBTL1 1860/4885ATM 2983/4885
US-20210057653-A1 ORGANIC COMPOUND AND PHOTOELECTRIC CONVERSION ELEMENT CRY1, CYP1A1, CCNE2 KDM4E 1730/4885L3MBTL1 1860/4885ATM 2983/4885
US-10868260-B2 Organic compound and photoelectric conversion element CRY1, CYP1A1, CCNE2 KDM4E 1730/4885L3MBTL1 1860/4885ATM 2983/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.